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Biomedical subjects

J Fabia

Publications and source records attributed to J Fabia.

29 records · Page 2Linked to original sources
PubMed1977

Recent time-trends of age-specific death rates for breast cancer: Quebec and other provinces, 1965 through 1974.

For the 10-year period 1965 through 1974 the age-specific death rates for cancer of the breast decreased among middle-aged women, especially at ages 40 to 49 years, in Quebec, the Maritimes and the Prairies but not in Ontario or British Columbia. In women under 35 years of age the mortality generally increased, while in women aged 60 to 64 years there was little change except in the Prairies, where the rate increased. It seems probable that the trends reflect changes in incidence rather than in case-fatality. Some, but not all, of the pattern could be explained by changes in fertility over the past 50 years.

Adolescent↗
PubMed1976

Survival in breast cancer: study of 283 patients.

Records of 283 women with breast cancer diagnosed from 1965 through 1973 at l'Hôpital du Saint-Sacrement were studied for survival at 3 and 5 years. These were all patients who had not previously received cancer-directed treatment. Life-table methods based on full intervals only were used to analyze survival. Adjustment for deaths from other causes was provided by computing the expected and relative survival rates. The 5-year relative survival rates (%) were 60.2+/-4.1 for the total group of 283 patients, 87.9+/-4.5 for the 142 with localized disease and 44.9+/-59 for the 118 with regional spread. Of the patients with disease that was either localized or regional, 84% underwent total mastectomy. The age of patients at entry did not differ from that of cases reported to the Quebec Tumour Registry. The significant increase over time in the proportion of patients with localized disease would be expected to reduce the Quebec death rate from breast cancer in future if the better survival of these patients is not simply a function of earlier diagnosis.

Adult↗
PubMed1975

Carotid endarterectomy: survival rates of 227 patients.

From March 1963 to March 1974, 227 patients with carotid stenosis underwent unilateral or bilateral carotid endarterectomy at l'Hôpital de l'Enfant-Jésus in Québec. Survival during the first 7 years after operation was analysed by life-table methods based on full intervals. The observed probability of death in this group was significantly higher than the probability expected in the general population, by 6.8% in the 1st year and 3.9% in the 2nd year. In the next 3 years the differences were much smaller (0.5, 0.9 and 1.4%). The major causes of death were myocardial infarction and stroke. Women fared somewhat better than men after the 1st year of follow-up. Unexpectedly, patients who underwent unilateral endarterectomy had lower survival rates in each of the first 5 years after operation than patients who underwent staged bilateral operations, whether survival was measured from the date of the first or the second operation.

Adult↗
PubMed1973

[Smoking in pregnancy, birth weight and perinatal mortality].

This study is based on a 10% random sample of medical certifications of birth in Quebec in 1970-71 and on additional information obtained from perinatal death certificates and birth registrations. Smoking in pregnancy significantly reduced the average birth weight after 35 weeks of gestation. It increased the risk of perinatal death by 24%. This increase was concentrated in the age groups under 25 and 35 +, in the parity groups 0 and 4 + and among women with less than 12 years of schooling. The proportion of mothers smoking during pregnancy was 43.2% and ranged as high as 62.2% among those under 20 with less than eight years of schooling. These depressingly high percentages imply that new educational approaches aimed particularly at high-risk groups should be developed and evaluated.

Adult↗
PubMedDate not supplied

Smoking during labour.

Smoking in hospitals is now forbidden. In several hospitals, however, women in labour are allowed to smoke in designated smoking areas. This study assesses whether smoking during labour increases the carboxyhaemoglobin concentrations in maternal and cord blood, taking into account the number of cigarettes smoked during pregnancy, duration of labour and parity. Women were questioned on their smoking behaviour shortly after delivery. A total of 295 mother-infant pairs were included in the study. Of the 94 (31.9%) smokers, 33 smoked during labour at home only and 34 during labour at the hospital. For newborns of smokers, the daily ration of cigarettes smoked by the mother during pregnancy and the number smoked during labour explained respectively 10.4% and 10.8% of the residual variance of carboxyhaemoglobin in cord blood. Smoking during labour significantly increases carboxyhaemoglobin levels. It should be prohibited in hospitals.

Blood Specimen Collection↗