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Biomedical subjects

J Favier

Publications and source records attributed to J Favier.

9 recordsLinked to original sources

Head injuries in children: a chronicle of a quarter of a century.

Children aged 0-15 years hospitalized in Geneva for head trauma during the last quarter of a century are reviewed. More than half of the severely injured children were not from Geneva area. New methods of management have been introduced progressively. The cases are divided in four successive time periods and classified according to their pathology. A continuous improvement in mortality is obvious, decreasing from 29.4% to 2.2%, but climbing again to 15.2% in the last period, probably due to more severe pathologies. For the Geneva area the mortality decreased progressively from 10.4/100,000 to 3.5/100,000 annually, due to better organization and management, but also to a drop in the incidence of severe cases from 35.5-13.5/100,000 per year. A decrease in the number of traffic accidents is responsible for this. However, the number of handicapped children has not changed.

Accidents, Traffic

Oligodendroglial tumors in childhood.

A series of 20 hemispheric tumors in children less than 16 years of age, over a period of 20 years, is presented. Among them, 8 were oligodendroglial tumors, a proportion well above the level reported in the literature. The World Health Organization (WHO) classification, which includes mixed oligoastrocytomas, in the oligodendrogliomas was used. This addition does not explain this unusually high proportion. Selection of cases and the correct histological diagnosis are probably important.

Adolescent

Brain specific gravity and CT scan density measurements after human head injury.

White matter specific gravity was measured using the microgravimetric method in 20 comatose patients with diffuse head injury who were undergoing intracranial pressure (ICP) monitoring, and in 19 patients with focal injuries who were undergoing evacuation of contusions or intracerebral hematomas. Computerized tomography (CT) density readings were obtained for each site of white matter sampling by locating the sampling site on the preoperative CT scan. A significant correlation was found between the specific gravity values and the CT density numbers (r = 0.775; p less than 0.001). Patients with focal injuries demonstrated reduced perifocal specific gravity, suggesting brain edema. The mean specific gravity in patients with diffuse injury was within the normal range. In 10 of 12 patients in whom the specific gravity was above the normal range, the CT density was also above the normal range. These data suggest that cerebral vascular engorgement is the cause of the high specific gravity. Six (60%) of this small subgroup of 10 patients also demonstrated a high ICP.

Adult

Breech delivery.

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Anesthesia, Obstetrical