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J Feigelson

Publications and source records attributed to J Feigelson.

At least 37 records · Page 2Linked to original sources

Additional data on hepatic function tests in cystic fibrosis.

Fifty cystic fibrosis (CF) patients, of whom 9 had multilobular cirrhosis, were observed regularly for a period of 3 years and various liver function tests, indicating cytolysis, cholestasis and cellular insufficiency were performed. Immunoglobulin and prothrombin were assayed. In 9 patients with cirrhosis, the tests were generally abnormal. Two distinct biochemical patterns of cirrhosis were distinguished, one clearly cholestatic and the other of a more cellular type. The distinction was made on the basis of the IgA : Transferrin ratio and of gamma-glutamyl-transpeptidase levels. In the non-cirrhotic patients, a temporary increase of cytolysis and cholestasis was observed in 50% of the cases.

Adolescent↗

[Coprologic anomaly in mucoviscidosis. Presence of albumin in low concentration in the feces].

With an immunological technique, presence of albumin was searched in the stools of 47 patients with cystic fibrosis and 54 controls. Albumin was found in 93% of cystic fibrosis, at a mean level of 90 mg/100 g of fresh stools. The test was negative in the 54 healthy controls. It was positive in one case of congenita IgA deficiency and in one untreated case of Hirschprung's disease. When found in the stools, albumin may give a useful additional diagnostic element.

Adolescent↗