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Biomedical subjects

J Finn

Publications and source records attributed to J Finn.

18 recordsLinked to original sources
PubMed1996

Does exposure to immunosuppressive therapy increase the 10 year malignancy and mortality risks in rheumatoid arthritis? A matched cohort study.

Rheumatoid arthritis (RA) is associated with increased mortality and an increased risk of neoplasms of the immune system (NIM). To establish whether immunosuppressive therapy alters these risks, a matched cohort study was conducted. The exposed cohort were 259 RA patients, resident in the UK, who first received immunosuppressive drugs (mainly azathioprine, cyclophosphamide and chlorambucil) between 1979 and 1982. The unexposed cohort were 259 patients matched for age, sex and disease, resident in the USA, who had never received immunosuppressives. Both cohorts had no prior reported malignancies and were followed for 10 yr. There was a small increase in mortality in the exposed compared to the unexposed cohort. Most of the excess deaths were due to malignancy. The relative risk (RR) of developing malignancy [1.5 (95% CI 0.9-2.3)] was lower than the RR of dying from malignancy [4.2 (95% CI 1.7-10.0)]. The RR of developing a NIM in the immunosuppressive-exposed group was 7.0 (95% CI 0.9-56.5). These results may be explained in part by differences in cancer registration and death rates between the UK and the USA. Nevertheless, the results suggest that exposure to immunosuppressive therapy increases the 10 yr malignancy risk in RA, but not mortality from other causes.

Adult↗
PubMed1995

Leininger's model for discoveries at The Farm and midwifery services to the Amish.

This paper is a descriptive report and analysis of a transcultural nurse's experiences immersed in a hippie subculture at The Farm near Summertown, Tennessee. This subcultural group initially was established over 20 years ago as a community with a unique worldview which included pacifistic, vegetarian, and collective values and beliefs. This community prefers health care provided by their own community members who serve as generic care providers and also as folk midwives for home births. Leininger's (1991) Theory of Culture Care Diversity and Universality and her Sunrise Model provided the framework for discovering and understanding this unique subcultural group. The major components of Leininger's Sunrise Model including worldview, cultural values, and lifeways were used in the analysis. The important social structure factors discovered included environmental context, technological factors, religious and philosophical factors, political and legal factors, economic factors, and educational factors. The Farm community's culture care expressions, patterns and practices for health and well being were discovered including generic and folk systems of care. The farm midwives provide primary care and home birthing care to a nearby Old Order Amish community. The Amish culture and health care seeking patterns are discussed including their selective use of generic, folk, and professional care systems. The discoveries that resulted from the application of Leininger's Sunrise Model are presented including implications for transcultural nurse caregiving.

Christianity↗
PubMed1994

Comparison of dietary intake methods with young children.

To select a valid method for obtaining dietary intake of preschool children, food intake of 17 children (8 in daycare programs and 9 in home care) was measured for three days. Each day, home caregivers and daycare staff were asked to recall what the child had eaten during the previous 24 hours. After the third day, the Willett Food Frequency Questionnaire was administered to assess intake during the preceding seven days, which included the three days of measured foods. There were no significant differences between means from measured and recalled intake. Although the children's gender and care status (daycare versus home care) made no difference in measured intake, there were significant differences in recalled intake for energy and percent of calories from saturated fat. In this study the questionnaire did not provide an accurate assessment of measured intake and could not replace the dietary recall.

Child Day Care Centers↗
PubMed1993

Effect of prolonged nifedipine or captopril therapy on lymphocyte magnesium and potassium levels in hypertension.

The effect of prolonged treatment with calcium channel blockers on potassium and magnesium stores is uncertain. We measured lymphocyte and serum magnesium and potassium in 28 patients treated for hypertension for 6 months with nifedipine or captopril. There was no difference in serum or lymphocyte concentrations in the two groups compared to 45 healthy, normotensive controls. These results suggest that intracellular cation levels are maintained with prolonged therapy with calcium channel blockers.

Adult↗
PubMed1992

Effect of captopril therapy on lymphocyte potassium and magnesium concentrations in patients with congestive heart failure.

Lymphocyte potassium and magnesium were measured before and 3 months after the introduction of captopril in 18 patients taking diuretics for congestive heart failure. Compared to 32 healthy controls, 9 patients who had been on potassium supplements plus frusemide had decreased baseline lymphocyte magnesium and potassium concentrations (p less than 0.01), in spite of similar plasma electrolyte levels. There was a significant (p less than 0.01) increase in both lymphocyte potassium and magnesium levels after 3 months' treatment with captopril and frusemide in these patients. Nine patients who had been taking a potassium-sparing combination diuretic also had an increase in lymphocyte magnesium (p less than 0.05) following the introduction of captopril. Increased intracellular potassium and magnesium may be one mechanism whereby angiotensin-converting enzyme inhibitors reduced arrhythmias and improve survival in patients with congestive heart failure.

Adult↗
PubMedDate not supplied

Detecting jaundice.

Explore the source record for details and available documents.

Humans↗
PubMedDate not supplied

Transcultural nurses reflect on discoveries in China using Leininger's Sunrise model.

This paper is a descriptive report of transcultural nursing discoveries in China. The authors embarked on this study tour led by an experienced transcultural nurse educator which presented a challenging opportunity to discover Chinese culture, lifeways, and health care systems. The authors were challenged to learn about cultural differences and the importance for nurses to use transcultural nursing principles and the Culture Care Theory with research findings about diverse cultures. Leininger's (1991) Theory of Culture Care and Sunrise Model were the conceptual and theoretical guides used to discover the worldview, lifeways, and cultural values of the Chinese people. The Sunrise Model depicts the components of a culture which include worldview, cultural and environmental context, and seven social structure factors. Analysis of these dimensions of the Sunrise Model enabled the authors to discover the important values, beliefs, and lifeways of the Chinese people. Religious and philosophical, kinship and social, political and legal, and economic factors were most important for this culture. In addition culture care expressions, patterns, and practices for health and well being were highly valued by this culture. The Sunrise Model includes diverse health systems which offer generic, folk, and/or professional care. The Chinese culture includes a strong reliance on folk health care systems which persists today. This paper discusses the simultaneous use of folk and professional health care by the Chinese people and implications for transcultural nurses.

China↗