[Rare disorders of the heart atrium in the echocardiographic picture].
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Biomedical subjects
Publications and source records attributed to J Fiserová.
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75 patients who had been operated between the ages of 3 and 17 years for juxta- or postductal coarctation of the aorta were investigated 11.2 years (1-19) later, when they had reached the mean age of 22 years. In 10 patients (13%) there had been an associated cardiac defect. Of the 65 patients without cardiac complications, 10% showed normal physiological values and 64% showed satisfactory results of surgery. There was moderate hypertension in 18% of the patients and in 6 (10%) there was a pressure gradient between the upper and lower extremities greater than 15 mm Hg. Aortography revealed recoarctation in only 3 cases (5%). The electrocardiogram was abnormal in 48% of the patients. Chest films showed the presence of specific and nonspecific signs of coarctation in 89% of the cases. Hemodynamic investigation by radiocirculography showed normal values in most instances.
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The substance under study was employed in 9 patients with a far-advanced lesion. Dosage of 7.5 mg/m2 of the body surface failed to render any effect, whereas 15 mg/m2 induced partial regression in 2 patients and stabilization of the process in another 2 patients. Some toxic phenomena were noted on the part of the digestive tract.
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