Analgesia for pelvic brachytherapy.
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Biomedical subjects
Publications and source records attributed to J Fitz-Henry.
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The study of midwives' occupational exposure to nitrous oxide in a poorly ventilated maternity unit in 1992 was instrumental in ensuring that the replacement building had Department of Health approved ventilation. We have repeated the study in the new unit. There was a trend for 8-hour time weighted average exposure to nitrous oxide to be lower in the new building. This difference was significant amongst those midwives who spent a greater time looking after women using Entonox and thus were more at risk from its detrimental effects. We discuss these findings and the ramifications for other maternity units under the new COSHH regulations.
Changes in basic haemodynamic variables following a sudden increase in the concentration of inspired desflurane administered during anaesthesia were compared in 30 female smokers and 30 nonsmokers. Smokers had significantly greater percentage increases in heart rate (p = 0.02), systolic and diastolic blood pressure (p < 0.005 and = 0.01, respectively) and rate-pressure product (p < 0.005). Such increases were reached faster by smokers for both systolic and diastolic blood pressures (p < 0.01) and for rate-pressure product (p = 0.02). The peak values of rate pressure product reached were sufficient to warrant caution when using desflurane for anaesthesia in smokers.
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