Biomedical subjects
Publications and source records attributed to J Fitzharris.
We report a case of endocarditis due to Pasteurella dagmatis complicated by vertebral osteomyelitis in a 55-year-old former alcoholic woman. To our knowledge, this is the second report of endocarditis attributed to that organism in the English-language medical literature. Rare cases of endocarditis due to other Pasteurella species and their varied clinical features are summarized.
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Overdose with 300 mg of nifedipine in a 54-year-old woman led to profound hypotension and reflex tachycardia. The patient was treated with intravenous fluids, calcium gluconate, and dopamine. Cardiac rhythm disturbances, hypoglycemia, and myocardial depression were not found. Recovery was rapid and uneventful. The clinical aspects of nifedipine overdose are discussed and possible treatment modalities are given.
Age-related alterations in plasma levels of beta-endorphin (BE) were investigated in young and aged human males. This was accomplished by obtaining repeated measurements of BE levels in the plasma of young and aged human male subjects during the morning hours, when a diurnal elevation of BE in the plasma is reported to occur. BE was extracted from the plasma and measured by radioimmunoassay. No differences were found in plasma levels of BE between young and elderly males at any time during the time period studied. In addition, the mean level of BE in the plasma during the entire sampling period did not differ between the two age groups. These data suggest that in human males, the levels of BE in the plasma during the morning hours are not modified by aging.
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