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Biomedical subjects

J Flamm

Publications and source records attributed to J Flamm.

15 recordsLinked to original sources
PubMed1979

[Recurring urothelial tumours of the urinary tract (author's transl)].

Problems of diagnosis, therapy and prognosis of recurring urothelial tumours of the urinary tract are discussed on the basis of six cases. An urothelial tumour can be considered as a local manifestation of general disorder of the mucosa of urinary tract and therefore every patient with such a tumour has to undergo regular X-ray and endoscopic checks of the whole urinary tract, even if the tumour has been radically operated. Among 38 urothelial tumours of the upper urinary tract there were 6 recurring tumours (15.7%) at different sites and of varying malignancy. Descending and ascending tendencies of spread were observed.

Aged↗
PubMed1979

[An urodynamic study of patients with benign prostatic hypertrophy treated conservatively with phytotherapy or testosterone (author's transl)].

Conservative therapy of benign prostatic hypertrophy comprises the administration of oestrogens, gestagens, androgens and anti-androgens. Phytodrugs, which contain an extract of Sabal serrulatum or Pygeum Africana as active substance are without side effects and are, therefore, being used increasingly. 74 patients with irritable or obstructive bladder symptoms due to benign prostatic hypertrophy were treated with a phytodrug (Sabal serrulatum) or with testosterone throughout a period of three months. In group one (20 patients given phytodrugs and 10 patients given testosterone) clinical symptoms and measurements of residual urine, residual urine quotient, bladder capacity, micturition pressure and maximum urethral closure pressure were recorded at the beginning and at the end of therapy. In group two 28 patients were treated with the phytodrug in the first and third months with an intervening placebo trial lasting four weeks and 16 patients were given testosterone. Clinical symptoms and uroflow and residual urine only were charted in this group. None of the patients in either group showed an improvement in the urodynamic parameters of obstruction, but all patients felt a subjective alleviation of their symptoms.

Aged↗
PubMed1979

[Follow-up angiography after palliative renal artery occlusion with the GAW-(Gianturco-Anderson-Wallace)-spiral (author's transl)].

Follow-up angiograms were carried out in six patients after palliative renal artery embolisation for hypernephromas using a GAW-spiral. The following conclusions were reached: it is possible to obtain complete occlusion of the renal artery with cessation of haematuria, reduction in tumour size and in the extent of the pathological vessels. It is necessary, however, to place the spiral accurately in the vessel to be occluded and to embolise all major arteries supplying the tumour. Even when the renal artery has been completely occluded, tumour growth results in the development of varying extent. In order to reduce this collateral circulation, vessels to the tumour periphery should be embolised with a suitable substance before spiral occlusion is carried out.

Adenocarcinoma↗
PubMed1979

[Treatement of malignant renal tumors by selective embolization of the renal artery (author's transl)].

The embolization of tumors in the treatment of hypernephromas is discussed on the basis of 13 cases. The method involved the use of three different substances: thrombin (Topostasin), homogenized muscle pulp, and fibrin from the patients own body, 600 units of thrombin being subsequently injected. In each case the embolization material was introduced into the tumorous kidney via an indwelling terminally open Kifa catheter after preoperative selective angiography. A differentiation is made in the indication between prophylactic embolization, which is performed preoperatively to prevent extensive hemorrhaging and increased tumor cell dissemination, and curative embolization applied in the case of patients presenting a greatly increased operation risk, inoperable tumor, or large-scale hematuria. The paper discusses the course of the treatment, possible complications, and postembolization in terms of case histories. The fibrin-thrombin method, beause of the small expenditure of time and technical resources involved, presently appears to be most favorable form of renal tumor embolization. Other methods are discussed on the basis of the literature.

Adenocarcinoma↗
PubMed1979

[Multicentricity of urothelial tumors of the efferent urinary tracts].

On the basis of 8 cases with primary urothelial tumours of the upper efferent urinary tract with simultaneously only partly preoperatively diagnosed secondary tumours of the urothelium the problems of diagnostics and therapy are discussed. A conservative surgery may be regarded as sufficiently radical only then when a multicentric genesis may be excluded with certainty. In our patients with tumours of the upper efferent urinary tract we found a multicentricity in 18.4%.

Aged↗
PubMed1978

[Isolted spermatic cord tuberculoma (author's transl)].

A case is reported of the postoperative recognition of an isolated tuberculoma of the left pampiniform plexus. This is only the seventh recorded case of an isolated spermatic cord tuberculoma. The findings are interpreted on the basis of the histological report. This case is discussed within the framework of urogenital tuberculosis as an entity according to reports in the literature.

Female↗
PubMed1978

[Clinical and immunologic investigations of patients with urinary bladder tumors (author's transl)].

Forty patients with urinary bladder tumors (26 cancer and 14 papilloma) were investigated by clinical and immunological methods. Patients with Stage I and II bladder cancer had a decrease in their delayed cutaneous hypersensitivity reactions in comparison to healthy controls. The same was found in patients with proliferating papillomas (WHO I) and benign papillomas. Patients with carcinoma in Stages III and IV had a reduced reactivity to recall antigens and could be immunized to a significantly lesser degree with primary antigens. In most cases a transurethral resection of the tumor was followed by radiotherapy. In four patients local immunotherapy was performed after resection of most of the tumor mass.

Carcinoma↗
PubMed1978

[Hypertrophy of the internal urethral sphincter in children (author's transl)].

On the basis auf 2 cases congenital hypertrophy of the internal urethral sphincter the authors discuss problems of diagnosis and therapy. They attribute great importance particularly to the urodynamic approach in the assessment of disorders of urinary flow in children. Compared with static or non-physiological methods, such as endoscopy or retrograde urethrography functional diagnostic methods like uroflow, manometry and MCU have definite advantages, precisely where it is a matter of analysing functional disorders. However, if the child is to be spared protracted obstruction of urinary flow, early diagnosis is a prerequisite.

Diagnosis, Differential↗
PubMed1977

Treatment of the neurogenic bladder with direct current on the spinal cord (Myelotron).

We carried out urodynamic examinations before and after galvanotherapy (Myelotron) of the spinal cord in 25 patients with upper and lower motor neuron lesions, mixed lesions and sensory lesions of the bladder. With the upper motor neuron lesions (neurogenic unhibited bladder, dyssynergia) there was a deterioration of the condition and therefore electrotherapy is contraindicated in this group of patients. With the lower motor neuron lesions and also the sensory lesions definite success was achieved with electrotherapy. Where there is a deficiency of impulses, it would appear to be compensated.

Adult↗
PubMed1977

[Percutaneous direct current treatment (myelotron) of neurogenic bladder disorders due to injuries of the lower motor neurons].

We examined 18 patients with lesion of the lower motor neuron, conditioned partly by lesion of the spinal cord, partly by lesion of the peripheral vesical nerves, before and after the percutaneous electrostimulation (myelotron) and established the urodynamically verified effect. Apart from one case of unclarified and fully therapy-resistent atony of the urinary bladder we found in all patients a subjective improvement of their complaints (retarded beginning of miction, spontaneous miction only with straining, large quantities of residual urine). Objectively an improvement of the sensitivity of the urinary bladder or of the motoricity appeared, in most cases both. We could not establish an essential influence on the tonus of an empty bladder and the tonus of the sphincter musculature. In all patients the residual urine could be reduced drastically, after the treatment the major part of the patient could urinate without residual urine.

Adult↗