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Biomedical subjects

J Flannery

Publications and source records attributed to J Flannery.

49 records · Page 3Linked to original sources

Toward integrating psyche and soma: psychoanalysis and neurobiology.

The brain is the "key organ" for understanding mind/body/illness relationships. During the past two decades neurobiological research has generated a plethora of new data and concepts which have increased tremendously our knowledge of the functioning brain. As a result the psychoanalytic view of the relationship between mind and brain may seem at risk of becoming outmoded. Yet while psychoanalytic theory may no longer be wholly tenable, psychoanalysis continues to offer interesting and heuristically valuable isomorphic models of cortical function. On the other hand neurobiology provides a corrective influence on psychoanalytic concept-building, causing theory to be refined as it is tested against the results of research. One possible result of interdisciplinary cross-fertilization is that a revised theory of the function of dreams and fantasy may throw light on the vicissitudes of somatic experience, and the pathogenesis of psychophysiological disorder.

Brain↗

Serotonergic and catecholaminergic influence on thyroid function in the vervet monkey.

Vervet monkeys were pharmacologically treated acutely and with repeated dose loading to alter serotonergic systems to assess the role of serotonin in the regulation of the hypothalamus-pituitary-thyroid axis. Acute L-tryptophan administration failed to alter basal levels of thyroid hormones but did decrease the TRH-induced TSH response. Repeated dose loading of tryptophan or 5-hydroxytryptophan increased blood serotonin and plasma T3 and decreased plasma TSH. The tryptophan hydroxylase inhibitor p-chlorophenylalanine yielded decreased blood serotonin, but did not affect plasma TSH, T4 or T3. The monoamine oxidase inhibitor chlorgyline also resulted in increased blood serotonin, but increased plasma TSH and T4 and decreased T3. These data may be explained by a unitary hypothesis involving central catecholaminergic, rather than serotonergic, control of TRH release. Chlorgyline may produce its effects predominantly by facilitating catecholaminergic stimulation of TRH release resulting in increased TSH and a consequent increase in T4. It is suggested that the effects of tryptophan and 5-hydroxytryptophan result from increases in serotonin levels in the thyroid gland to produce an increase in T3 with a compensatory decrease in TSH via negative feedback. The differences observed between the acute and repeated dose loading studies stress the need for both types of studies before drawing conclusions about the effects of pharmacological manipulations on hormonal levels.

5-Hydroxytryptophan↗

Malignant melanoma in Connecticut and Denmark.

The rising incidence of malignant melanoma of the skin was reviewed using data from the Connecticut Tumor Registry (1935-1974) (Eisenberg et al., 1967) and the Danish Cancer Registry (1942-1972) (Clemmesen, 1965, 1974, 1977). A total of 7,530 cases were analyzed according to age, sex and anatomic site. The total age-adjusted incidence rates were similar for these two countries, despite geographic and demographic differences. HOwever, the most rapid changes in melanoma incidence were observed in females from Denmark and males from Connecticut. In addition, the largest increases occurred for lower-extremity lesions in Danish middle-aged women and trunk-neck melanomas in Connecticut middle-aged men. Melanoma of the face was resistant to changing incidence and occurred in an older age group than melanoma of other skin sites. In general, birth cohort analysis confirmed that changing incidence began for persons born around 1900, but the rising incidence for lower-extremity melanomas in women and trunk-neck melanomas in males began earlier. In comparing incidence for anatomic sites by correcting for surface area and melanocyte density, higher than expected rates were seen for melanoma of the face in both sexes and trunk-neck melanoma in the males. The data presented support the concept that a cumulative exposure to solar radiation may be important in the etiology of melanoma of the face, but short-, intense sun exposure is probably related to melanoma in other sun-exposed areas, and that melanoma in areas other than the face is responsible for the rising incidence of this disease.

Adult↗

Education for rehabilitation nursing.

An increasing shortage of rehabilitation nurses is anticipated in the coming decade. This article describes one potential answer to the nursing shortage through a course in rehabilitation nursing for senior baccalaureate students. The unique features of the course included the use of holistic learning experiences that integrate theory and practice. Clinical experiences in critical care units, in intensive rehabilitation settings, and in a variety of outpatient facilities, as well as travels with rehabilitation nurse consultants in the field, provided students with rich perspectives on the scope of rehabilitation nursing practice. Replication of this successful course in other settings has the potential to enhance the recruitment of new graduates into the field of rehabilitation nursing.

Education, Nursing, Baccalaureate↗

Focus on excellence: decision making in rehabilitation nursing.

This article describes the conceptual framework, design, implementation, and evaluation of a series of workshops for rehabilitation nurses in which the Decision Profile, a practical model for clinical decision making, was used. Evaluations confirmed that the approach was exceptionally effective, not only in engaging the audience and presenting information that would assist in continued professional development, but also in validating and supporting the participants' intuitive processes and decision-making patterns through analyses presented by experts.

Adult↗

Using the levels of cognitive functioning assessment scale with patients with traumatic brain injury in an acute care setting.

The levels of Cognitive Functioning Assessment Scale (LOCFAS) is a behavioral checklist that includes behaviors commonly seen in patients during the earliest stages of recovery from traumatic brain injury (TBI). The LOCFAS and the Disability Rating Scale were used four times each week to evaluate 28 patients who had had TBI; this was done throughout their acute care hospitalization. The Glasgow Coma Scale, Stover-Zeiger Scale, and Expanded Glasgow Outcome Scale also were used to evaluate patients at their initial assessment and at the time of their discharge. Concurrent validity (r > .85), both at the initial assessment and discharge, and predictive validity (r > .70) were high. The daily stability and interrater reliability (r = .99) of the LOCFAS also were good.

Acute Disease↗

Meeting the needs of rural families during critical illness: the APN's role.

Family needs during critical illness have been a major focus of nursing research, yet the unique needs of families living in rural America still need to be investigated. This study sought to identify the needs of families in rural southern Appalachia and compare these findings to those from a study that identified the needs of families in a large metropolitan medical center. We found 13 needs to be significantly different between the rural and urban samples and suggest strategies that rural and urban critical care nurses and advanced practices nurses can use to care for families of critically ill patients from rural areas.

Appalachian Region↗

The student process for success: the nursing care plan.

Written nursing care plans are designed to focus students on individualizing nursing care, which promotes critical thinking and decision making. In actual practice, emphasis has shifted from care plans toward standards of care. The authors discuss a concise, simplified care plan format that includes both standards of care and collaborative problems. This plan of care is compatible with healthcare regulations and requires less time to produce and evaluate.

Clinical Competence↗