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Biomedical subjects

J Forfa

Publications and source records attributed to J Forfa.

4 recordsLinked to original sources
PubMed1995

[Evaluation of acceptance rate and outcome of renal replacement therapy in patients with diabetic nephropathy--multicenter study].

Development of dialysis methods and progress in kidney and pancreas transplantation allowed to treat an increasing number of patients suffering from diabetic nephropathy (D.N.). This report evaluates availability and results of treatment in these patients. 31.12.93 in Gdansk and Bydgoszcz area there were treated 519 patients, including 43 (8.2%) with D.N. It is impossible to evaluate the demand for renal replacement therapy in patients with D.N., because there is no exact data concerning diabetic patients with progressing renal failure. Up to now 88 patients with D.M. (68 with IDDM, 20 with NIDDM) were treat in this area. Most of them (92%) were treated with hemodialysis is and only a few with CAPD, 13 patients received a kidney graft. The average patient survival on dialysis treatment in NIDDM patients was 15 months and in IDDM patients was 11 months. Deaths were mainly caused by cardiovascular complications. The results of renal replacement therapy in these patients cannot be compared with data from other re ports, because the treatment was introduced at advanced stage of D.N. in patients with systemic complications (serum creatinine in IDDM was 9.7 md% and in NIDDM was 6.2% mg%). Following conclusions can be drawn from our observations: 1. There is a need for close cooperation between diabetologist and nephrologist in repeat of evaluation of the demand for renal replacement therapy and time for its institution in a particular patient. 2. The choice of method of renal replacement therapy depends on clinical findings in a particular patient but also on methods available in a particular center. 3. Improvement of therapy outcome can be achieved primarily by earlier institution of dialysis (serum creatinine below 5 m5%).

Adolescent↗
PubMed1991

[Effect of hemodialysis on left-ventricular contractility].

43 patients with end-stage renal failure maintained on hemodialysis were studied by echocardiography before and after hemodialysis. Considering possibility, that left ventricule can be enlarged due to intrinsic factors impairing their performance, like myocardial fibres damage in coronary disease or inflammation and extrinsic factors like hypertension, overhydration, anemia, arteriovenous shunt and humoral changes (electrolyte imbalance, uremic toxins, acidosis) three groups of patients were chosen: A--with normal left ventricular diameter, B--with enlarged left ventricule before and after dialysis, C--with enlarged left ventricule only before dialysis. Mean velocity of circumferential fibre shortening (mVcf) and ejection fraction (EF) as left ventricular contractility indexes and end-systolic meridional wall stress as afterload index were determined. Stress-shortening relations before and after hemodialysis were compared in groups, to determine possible intrinsic contractility impairment of the left ventricule. No differences in groups were found in preload reduction (weight loss) and humoral changes (BUN, creatinine, pH, potassium, calcium, hematocrit), also blood pressure was not significantly different in all groups. Hemodialysis improved contractility only in patients with normal left ventricular diameter and significant reduction of afterload. In group A and C stress-shortening relation increased after dialysis. In group B decreased probably because of the lack of mVcf improvement despite reduction of stress in two patients. It is possible that these two patients had impaired contractility and enlarged left ventricle due to intrinsic factors.

Adolescent↗
PubMedDate not supplied

[Microcomputer information systems designed to provide documentation about patients treated with dialysis].

A program specifically designed for PC/XT/AT compatible with IBM was written. This program is intended for collecting data on the patients treated with repeated dialyses. The system collects, edits, and surveys data according certain rules. It may print required data. It may also be extended by inclusion of the additional modules and adopted to other centres of dialysis. It is used for 2 years already and proved quite useful in the center of dialysis.

Data Collection↗