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Biomedical subjects

J Fouchard

Publications and source records attributed to J Fouchard.

87 records · Page 5Linked to original sources

[Stenosis of the main trunk of the left coronary artery. Apropos of 54 cases].

In the 54 patients studied coronary arteriography alone showed stenosis of the left main coronary artery (a lesion observed in 5.2 p. 100 of pathological coronary arteriographies), associated with other coronary lesions, 72.2 p. 100 of which involved all three major vessels. Ventriculography was abnormal in 53 p. 100 of the cases, with a less than 45 p. 100 left ventricular ejection fraction in 37.4 p. 100 of them. Nine patients were considered inoperable; 4 of these died during a 40-month follow-up period under medical treatment. Forty-five patients underwent coronary bypass; there were 4 peri-operative deaths (8.9 p. 100), 8 post-operative myocardial infarctions (17.8 p. 100) and one late death (2.2 p. 100). These patients were followed up for a mean period of 26.4 months. All authors who have studied the subject agree that surgery is beneficial: not only does it improve cardiac function, but it also prolongs survival. In spite of the peri-operative risks, surgery must be contemplated in patients with a more than 50 p. 100 stenosis of the left main coronary artery, provided the cardiac vascular bed is accessible to revascularization.

Arteriosclerosis↗

[Constrictive pericarditis and post-radiotherapy myocarditis with mitral incompetence (author's transl)].

The cardiac complications of radiotherapy of the thorax (e.g. for Hodgkin's disease and carcinoma of the breast) are various: 1) Pleural effusions, occurring a few months to two years after radiotherapy, spontaneously curable but may give signs of tamponnade or lead to constriction. 2) Constrictive pericarditis often several years after irradiation, with a poor prognosis in spite of attempts at pericardectomy which is indicated at the stage of hemodynamic constriction. 3) Myocardial involvement with advanced fibrosis and with various clinical presentations. The failure of pericardectomy and mitral incompetence were evidence of myocarditis in the case reported here.

Adolescent↗

[Complications of anticoagulant treatment. Report of 98 accidents and incidents (author's transl)].

According to an estimation on 1 587 patients under anticoagulant treatment, 84 of them have caught a therapeutic accident so a frequency of 5,3 per cent. It concerns 98 therapeutic accidents : 89 haemorrhagic spontaneous accidents (11 digestive haemorrhages, 5 cerebro-vascular accidents, 54 hematomas with 18 retro-peritoneals and 11 in musculis rectis abdominis, 9 hematuries, 2 serous haemorrhages, 8 various haemorrhages) ; 8 "induced" haemorrhages, in which 5 after arterial catheterism, and an accident allergic to the phenyl-indane-dione. Nine deceases were revealed : in which 5 are directly attributed to the hemorrhagic accident (3 cerebro-vascular accidents and 2 serous haemorrhages).

Aged↗

[Coronary embolism revealing mitral valve stenosis].

We report a case of myocardial infarction with normal coronary arteriography in a 39-year-old woman presenting with tight mitral stenosis complicated by atrial extrasystoles and spontaneous atrial contrast at echocardiography. The diagnosis of coronary embolism was most probable. Coronary embolism is a rare disease, usually due to a blood clot or, less frequently, to a vegetation of endocarditis starting in a heart valve. The left network is usually involved, with typical myocardial necrosis. Coronary arteriography is sufficient to make the diagnosis. Preventive treatment is essential.

Acenocoumarol↗