Biomedical subjects
Publications and source records attributed to J Friis.
A case with calcified periarthritis at peripheral sites and calcification in intervertebral discs gives support to the perception of a distinct disease entity as proposed by SANDSTROM. The possible significance of genetic factors is discussed.
A routine program for evaluation of the protein pattern in serum and synovial fluid has been tested on 25 patients in a consecutive study. The program comprised agar gel electrophoresis, total protein and albumin determination, and immunochemical determination of antitrypsin, orosomucoid, haptoglobin, IgR, and IgA. Linear correlation analysis of corresponding data in serum and synovial fluid gave r-values for the five latter components which varied from 0.74 to 0.87. On this basis reference intervals in synovial fluid could be established. Total protein, haptoglobin and IgG were elevated in rheumatoid arthritis, compared with osteoarthritis.
HL-A27 were found in 31 of 48 patients with Reiter's disease (65%) as compared with 8% of 2 103 health controls. It is suggested that HL-A27 is closely related to the inheritance of a special immune response leading to an increased susceptibility to a special type of reactive arthritis which Reiter's disease has in common with ankylosing spondylitis and a certain type of psoriatic arthritis.
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