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Biomedical subjects

J Frith

Publications and source records attributed to J Frith.

8 recordsLinked to original sources
PubMed2000

The use and perceived value of diabetes clinical management guidelines in general practice.

OBJECTIVE: To assess attitudes to and use of NSW Health Department (NSWHD) guidelines for the clinical management of diabetes mellitus by divisions of general practice, general practitioners, patients and allied health professionals. METHOD: A mail cross sectional survey of divisions of general practice and a series of focus groups of GPs, patients and allied health professionals, on extent of use and perceived usefulness of the NSWHD guidelines. RESULTS: Forty divisions had or recently concluded a diabetes shared care project. Thirteen out of the 31 diabetes projects with guidelines reported using the NSWHD guidelines. Nineteen divisions were aware of the NSWHD guidelines. While the general response to the guidelines in both the survey and the focus groups was positive, there were suggestions for modifications. Many respondents were not aware of the guidelines. CONCLUSION: Optimal use of the guidelines in general practice requires improved dissemination and an implementation strategy based not only on GP education but also systems to reduce barriers to implementation and to support better quality of GP care.

Attitude of Health Personnel↗
PubMed1999

Is it MS? Presenting symptoms and diagnosis of multiple sclerosis.

BACKGROUND: Multiple sclerosis (MS) is the most common chronic neurological disease in our community. OBJECTIVE: To discuss the presenting symptoms that suggest the diagnosis of MS and consider how to confirm the diagnosis and evaluate the differential diagnosis. DISCUSSION: There are protean presenting symptoms of MS but because of the distribution of pathology predominantly in the peri-ventricular region of the brain, certain symptom complexes are more common. With the recent availability of treatment for MS which has been demonstrated to slow the progress of the disease, the need for early diagnosis has become even more important.

Diagnosis, Differential↗
PubMed1997

Identification of adenine nucleotide-containing metabolites of bisphosphonate drugs using ion-pair liquid chromatography-electrospray mass spectrometry.

Bisphosphonates are synthetic pyrophosphate analogues, which are used as therapeutic drugs for the treatment of metabolic bone disorders. Some of these bisphosphonates can be metabolised in cells into non-hydrolysable nucleotide analogues. In this paper, we describe an ion-pairing high-performance liquid chromatography method that is compatible with negative ion electrospray mass spectrometry for the separation of these metabolites. Tandem mass spectrometry and collision-induced dissociation (CID) were used for identification of the metabolites. The CID mass spectra of bisphosphonate-adenine nucleotide adducts are very informative, because major fragment ions are formed by cleavage of the bisphosphonate moiety from the conjugate. The method was used for detection of the nucleotide metabolites of clodronate, tiludronate and etidronate in extracts from mammalian cells after treatment with bisphosphonates.

Adenine Nucleotides↗
PubMed1996

The use of role plays in teaching drug and alcohol management.

This is an evaluation of the use of role plays to teach drug and alcohol assessment and management skills to medical students as part of their general practice training. Role plays of 'real life' scenarios enable students to evaluate their own learning experiences. This method facilitates effective peer discussion of clinical and ethical issues with a high degree of acceptability to both students and teachers.

Alcoholism↗
PubMedDate not supplied

A behaviour management and life stress course for a group of mothers incorporating training for health visitors.

Six mothers of preschool children presenting behaviour problems attended a 10-week course on behaviour management and life stress run jointly by a clinical psychologist and a family health visitor. Results indicated benefits to the family in terms of changes in childrens behaviour, the development of friendship networks, and increased knowledge of and willingness to apply behavioural principles to current and potential child management problems. Treatment in groups required fewer professional hours per family than an equivalent individual service and served a training function for the family health visitor.

Behavior Therapy↗