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Biomedical subjects

J Fukal

Publications and source records attributed to J Fukal.

16 recordsLinked to original sources
PubMed1998

[Malignant melanoma of soft parts (clear cell sarcoma)--a rare case of multiorgan localization].

Malignant melanoma of soft parts (MMSP) is a rare tumor originally described by Enzinger in 1965 as clear cell sarcoma of tendons and aponeuroses because of its affinity to tenosynovial structures. Tumors are found predominantly at the extremities. First visceral case was described in 1993 in the duodenum. We describe the case of 64-years old man with malignant melanoma of soft parts in the stomach, in the pancreas, in the mesocolon, in the left thigh and in the left axilla. This patient was successfully treated surgically by the resection of the stomach, resection of the pancreatic head, extirpation of the tumor from mesocolon, from the left thigh and from the left axilla. In all these localisations the tumor was histologically and imunohistochemically proved to be MMSP (positivity: s-100 protein, vimentin, HMB-45 and negativity CK, EMA, desmin, actin). This multivisceral occurrence is extremely rare and according to the review of literature this is probably the first published case of MMSP in the stomach and in the pancreas.

Axilla↗
PubMed1991

[Hereditary nephropathy with signs of nephrotic syndrome].

The authors submit the description of two sisters with hereditary nephropathy, with symptoms of nephrotic syndrome. In the clinical picture dominated permanent anuria, rapid renal failure and death at the end of neonatal age. Histopathological findings classified the disease as infantile diffuse mesangial sclerosis. The third patient is a sporadic case of primary congenital nephrotic syndrome.

Female↗
PubMed1990

[Congenital nephrotic syndrome].

Only one case of congenital nephrotic syndrome was recorded in a series of 2,500 bioptic examinations of the kidney performed over a period of 20 years. In necroptic material examined over the same period of time congenital nephrotic syndrome was recorded three times. At the first bioptic examination of the kidneys only minimal changes of glomeruli were diagnosed. Rebiopsy exhibited proliferation of mesangial cells, focal segmental glomerular sclerosis, cystically dilated tubules in the juxtamedular region of the cortex, and focal tubulointerstitial reactive changes, which in accordance with the clinical findings were assessed as congenital nephrotic syndrome of the Finnish type. Comparison of the findings observed at the first biopsy and at rebiopsy demonstrates the importance of proper collection of a representative sample for renal biopsy.

Female↗
PubMed1989

[Thin-needle aspiration cytology of the thyroid gland].

A group of 187 fine needle aspiration cytology materials from thyroid gland was classified according to international cytology classification. The most important diagnostic criteria were presented for single lesions and correctness of cytologic evaluation compared with a complete bioptic finding.

Biopsy, Needle↗
PubMed1989

[Thin-needle aspiration cytology of the mammary gland].

Fine-needle aspiration cytology of the Mammary gland proved advantageous and reliable in a group of 387 cases (not any false positivity, 0.7 per cent false negativity). The method is especially usable for prebioptic diagnosis enabling cytostatic therapy before operation on evident carcinomas and for mammary screening.

Biopsy, Needle↗
PubMed1989

[Cytologic diagnosis of stomach lesions].

A group of 542 gastrofibroscopic cytological samples was compared with simultaneous gastrofibroscopic biopsy. The most important diagnostic criteria of single lesions derived from accepted cytological classification were discussed. Diagnostic value of cytology was advantageous.

Cytodiagnosis↗