PubMed Health⌕ Search

Biomedical subjects

J G Blythe

Publications and source records attributed to J G Blythe.

35 records · Page 2Linked to original sources
PubMed1982

Use of the bulbocavernosus muscle (Martius procedure) for repair of radiation-induced rectovaginal fistulas.

Radiation-induced fistulas of the vagina are rare, occurring in only 1 of 3% of patients treated for cancer of the uterine cervix. Primary surgical repair of these fistulas is usually unsuccessful because the defect is a result of devascularization. This type of radiation injury results from endarteritis obliterans, and successful repair requires an accessory blood supply. From 1971 to 1980, the authors performed 14 Martius procedures on 12 patients with radiation-induced rectovaginal fistulas. Eleven patients had successful closure of their fistulas using this procedure, and no operative complications occurred. The Martius procedure is effective for most radiation-induced vaginal fistulas, and the operation is well tolerated by most patients.

Adult↗
PubMed1980

Infectious morbidity after primary cesarean sections in a private institution.

Primary cesarean sections were performed on 395 patients between January 1, and December 31, 1976. A retrospective review of 322 of these patients indicated that the incidence of postoperative intrauterine infection was the same in both monitored and nonmonitored patients. The incidence of postoperative intrauterine infections was not significantly related to ruptured membranes or the duration of ruptured membranes. The most significant factor associated with postoperative morbidity was the type of anesthesia.

Adult↗
PubMed1978

Cervical bacterial flora in patients with gynecologic malignancies.

Radiation and gynecologic oncologists agree that pelvic irradiation in the presence of pelvic inflammatory disease, parametritis, or pyometra can be catastrophic. A temperature elevation in a patient having intrauterine radiation is very perplexing. This study was designed to investigate one of the three reported etiologies for this condition. Some investigators have suggested an exacerbation of a quiescent infection as a possible etiology because of the necrotic condition of many cancerous cervices. Aerobic, anaerobic, and fungus cultures were performed on 32 patients prior to intrauterine administration of cesium. The organisms cultured were similar to those identified as the normal cervical flora. The frequency of the organisms seemed independent of the amount of irradiation. The number of organisms cultured did not vary with the use or nonuse of cleansing vaginal suppositories. This study indicated no increase in bacterial growth in these cancerous necrotic cervices; also it did not indicate the growth of any unusual pathologic bacteria.

Adult↗
PubMed1978

Barogenic rupture of the esophagus associated with hyperemesis gravidarum.

Spontaneous rupture of the esophagus is associated with continuous nausea and vomiting in the chronic alcoholic. The following is a case report of a similar occurrence in a young, healthy, primigravida with hyperemesis gravidarum. To our knowledge, this has not previously been reported in the obstetric literature.

Adult↗
PubMed1978

Fibrin degradation products and the diagnosis of ovarian carcinoma.

This project was designed to determine if the presence of fibrin degradation products (FDP) in the blood are of value in the preoperative evaluation of patients with pelvic masses. This study comprised 120 consecutive patients who were evaluated for a diagnosis of pelvic mass, ovarian cyst, or ovarian carcinoma. A blood sample was drawn from each patient and fibrin degradation products were determined utilizing the Thrombo-Wellcotest. Platelet counts and partial thromboplastin time (PTT) were also determined on each patient. Ovarian carcinoma was present in 17 (14.2%) of the patients. The FDP was found in the serum of 16 (94.1%) of the patients with ovarian carcinoma. One (5.9%) of 17 patients with ovarian carcinoma had a negative FDP (less than 10 mg/ml). Eleven of the 120 patients (9.2%) had a positive FDP with no demonstrable etiology. A sample of fluid was obtained from two cystic ovarian carcinomas and when analyzed for FDP both samples were strongly positive.

Cystadenoma↗
PubMed1977

Retropsoas and subgluteal abscesses following paracervical and pudendal anesthesia.

Retroperitoneal abscesses are uncommon in obstetrics and gynecology. Recently, seven reported cases of retropsoas-subgluteal abscesses following paracervical-pudendal anesthesia have been reported, and we have seen two additional cases. The infrequent occurrence and diagnostic difficulties make these abscesses especially dangerous. They can result in substantial patient morbidity and mortality. They must be suspected in patients receiving paracervical-pudendal anesthesia prior to vaginal delivery in whom hip pain subsequently develops. Therapy consists of prompt surgical exploration and drainage and appropriate antibiotic therapy.

Abscess↗
PubMed1977

Bilateral Brenner tumors: a case report and review of the literature.

Although the first Brenner tumor was reported in 1898 by MacNaughton-Jones, it was not until 1907 that Fritz Brenner described the tumor that bears his name. Since then more than 500 cases have been reported with bilaterality ranging from 3.7 to 8.0 per cent. However, this percentage is probably high. The tumor was originally thought to arise from follicular epithelium. Several other etiologies of the Brenner tumor have been suggested, including celomic surface epithelium, Walthard rests, teratoma, urothelium, and rete ovarii. The majority of Brenner tumors are inert, but there have been reports suggesting endocrine activity. The question of malignant transformation of the Brenner tumor has gained attention since Von Numers described the first malignant Brenner tumor in 1945. The determination of malignancy of these tumors has been hampered by vague histologic criteria for malignancy. The confusion surrounding the histogenesis, hormonal capabilities, and malignant potential of the Brenner tumor has persisted. A case report of bilateral Brenner tumors of the ovaries is presented as well as a review of the literature with emphasis on the bilaterality of Brenner tumors.

Adult↗
PubMed1976

Fracture healing in estrogen-treated and castrated rats.

The healing of a midfibular fracture was studied in mature rats. The strength of the healing fracture was determined by a constant speed-driven tensiometer which measured the force required to separate the healing callus. The breaking strength of the healing experimental fracture was ascertained in control, estrogen-treated, and oophorectomized animals. The fracture strength was not significantly different in any of these groups.

Animals↗
PubMed1975

Bony metastases from carcinoma of cervix. Occurrence, diagnosis, and treatment.

Fifty-five patients treated for cervical carcinoma developed bony metastases between January 1, 1961 and December 31, 1973. Roentgenograms were diagnostic in all but 2 of the patients. In 15 patients, a combination of radioactive scans and roentgenograms was used to establish the diagnosis. The most common mechanism of bony involvement from carcinoma of the cervix was extension of the neoplasm from para-aortic nodes, with involvement of the adjacent vertebral bodies. The earliest metastases were discovered at the time of the primary diagnosis. Thirteen years was the longest interval from the primary diagnosis until the discovery of bony metastases. Sixty-nine percent of the patients were diagnosed within 30 months. Ninety-six percent of the patients died within 18 months. Seventy-six percent of the patients received some form of therapy for their metastases. Thirty-six of these patients were treated with radiation therapy. Four of these patients received complete relief of symptoms, 24 some relief, and 8 patients received no relief.

Adenocarcinoma↗