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Biomedical subjects

J G Clara

Publications and source records attributed to J G Clara.

26 records · Page 2Linked to original sources

[Ambulatory monitoring of blood pressure. Validation of a method].

Before the routine use of our ambulatory blood pressure (ABP) device, we did the correlation analysis of 153 pairs of blood pressure measurements within the ABP and gold-standard sphygmomanometer. We got a good correlation but a systematic statistical error about less 7 mmHg on systolic measurement and 11 mmHg on diastolic measurement by the ABP device. The different qualities found among the devices that we have in the market, lead to the proposal of protocols of validation in the premarketing and periodic quality assessment by the clinics.

Blood Pressure Determination↗

[Polypharmacotherapy in the elderly hypertensive patient].

We asked 53 elderly hypertensives from our outpatient clinic which and how many drugs they took, and analysed factors that could have affected the intake, as sex, age and school instruction. The most frequent drug groups found were, in decreasing order, antihypertensives, benzodiazepines, nitrates and non-steroidal anti-inflammatory drugs. 53.3% of the patients took only angiotensin converting enzyme inhibitors and/or calcium-channel antagonists as antihypertensive drugs. Twenty four patients used occasional medications, sometimes as much as 6 different drugs, specially analgesics, antipyretics and anti-inflammatory agents. These patients took, in mean, 5.2 different drugs daily, 2.1 of which antihypertensive, in a total of 8.5 pills. Females took more drugs (9.4 +/- 3.6 pills per day against 7.1 +/- 3.0 in the male gender, Z < 0.03). Age and school instruction did not affect the intake.

Age Distribution↗

[Arterial hypertension in the elderly. Experience at a hospital service].

High blood pressure in the elderly population is currently one of the most important public health problems. In recent years, a dramatic increase in life expectancy has occurred and cardiovascular diseases are now one of the major causes of morbidity and mortality in this age group. Therefore, high blood pressure in the elderly has been the aim of many trials throughout the world. In Medicine Department 1 of St. Maria Hospital, we designed and implemented a special outpatient follow-up for elderly people (> or = 65 years old) with hypertensive disease. At the end of the first year, 61 patients (22 men and 39 women) with an average age of 71 years (SD +/- 5.3), with known of high blood pressure for an average of 10 years were treated with angiotensin converting enzyme inhibitor (11 patients), calcium channel blockers (6 patients), or a combination of both drugs. The mean blood pressure fell 15 mm Hg (SD +/- 19.6) without deterioration of the renal function. The echocardiographic evaluation showed reduction in the left ventricular dimensions without significant modifications of diastolic, systolic and cardiac output. In addition, there was a significant increase in attention/concentration and memory abilities, however the percentage of depressed patients was the same at the end of the first year of treatment for high blood pressure.

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