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Biomedical subjects

J G Enad

Publications and source records attributed to J G Enad.

9 recordsLinked to original sources

Partial absence of pericardium in an endurance athlete. A case report.

A twenty-nine-year-old competitive endurance runner was noted to have a congenital absence of the pericardium on a routine screening exam. No recommendations for activity restrictions have been previously described for this condition. After maximal exercise performance on a cardiac stress test without symptoms of cardiac compromise and consultation with cardiologists and cardiothoracic surgeons, the patient was returned to full, unrestricted competitive running. Once the diagnosis of absent pericardium is confirmed by imaging modalities, cardiac stress testing may be employed to determine a recommended activity level for the patient.

Adult↗

Primary patellar tendon repair and early mobilization: results in an active-duty population.

We retrospectively reviewed 13 patellar tendon repairs done over 32 months at a tertiary care, military medical center. Early mobilization was initiated within 2 weeks postoperatively. Clinical and functional results were statistically examined with relation to age, timing of surgery, length of follow-up, quadriceps atrophy, extensor lag, patella position, and time to full duty. At an average of 24 months' follow-up, six patients (46%) had thigh girth atrophy, and one patient (8%) had an extensor lag >5 degrees. Mean Lysholm score was 84 (range, 57 to 100). Maximum postoperative Tegner activity scores averaged 7.1 (range, 5 to 10). Clinical results classified five cases as excellent, three good, three fair, and two poor. Functional results classified three cases as excellent, four good, two fair, and four poor. Time to return to duty averaged 13 months. Our results suggest that adequate extensor function can be restored after primary repair and immediate motion therapy.

Adult↗

Patellar tendon repair: postoperative treatment.

OBJECTIVE: To compare results of patellar tendon repair after early and delayed postoperative mobilization. DESIGN: Two separate treatment groups, comparing 2 treatment alternatives at different time periods (before-after trial). PARTICIPANTS: Postoperative rehabilitation of 10 men who underwent patellar tendon repair. INTERVENTION: Delayed mobilization group: weight-bearing in a cast and isometric lower-extremity exercises for 6 weeks; active flexion and extension exercises thereafter. Early mobilization group: weight-bearing in an extension brace, isometric lower-extremity exercises, prone active knee flexion, and passive knee extension for 6 weeks; active flexion and extension exercises thereafter. Sixteen-month minimum follow-up. RESULTS: Clinical (physical) findings were: 2 excellent, 1 good, 2 fair in the delayed-mobilization group; 1 excellent, 3 good, 1 fair in early-mobilization group. Functional (pain and activity level) findings were: 2 good, 2 fair, 1 poor in the delayed-mobilization group; 3 good, 1 fair, 1 poor in the early-mobilization group. CONCLUSIONS: Clinical and functional results were similar for both treatment groups. Further study is required to determine any significant long-term differences between rehabilitation methods.

Adult↗

Patellar tendon ruptures.

BACKGROUND: Isolated rupture of the patellar tendon is a rare injury. Often occurring during a fall in 20- and 30-year olds, patients may have a preexisting medical condition (eg, history of steroid use) or a history of repetitive microtrauma to the knee. A high-riding patella on physical examination and radiographs is pathognomonic. METHODS: Immediate orthopaedic referral for surgical repair is necessary to reestablish knee extension. Delay in diagnosis can make surgical treatment more difficult. Current methods of postoperative rehabilitation are evolving. RESULTS: Evaluative studies based on rating scales show satisfactory clinical and functional results after surgery. However, time lost from work and recreation may be protracted, and quadriceps atrophy is often evident. CONCLUSIONS: Ruptures of the patellar tendon should be diagnosed acutely and immediately referred to an orthopaedic surgeon. The impact of the injury to the patient may be long-standing even after operative treatment. Contemporary surgical and rehabilitative techniques give the best opportunity for restoration of functional activity.

Humans↗

A review of sternal wound complications in a military hospital.

A retrospective review of sternal wound complications was conducted during a recent 13-month period at the Naval Hospital, San Diego. These complications developed in 5 (3.0%) of 168 patients after they underwent coronary artery bypass with saphenous vein grafts. Three or more of these patients were male, obese, and hypertensive, with a significant smoking history. All these factors have been previously reported to be associated with an increase in the incidence of sternal wound complications. All patients had prolonged postoperative intensive care treatment, and ultimately all patients recovered and were discharged from the hospital. Interestingly, as opposed to other reviews, we were unable to show an association of sternal wound complications with the use of internal mammary artery harvesting.

Aged↗

Kaposi's sarcoma of the gallbladder.

A 30-year-old man with symptomatic acquired immunodeficiency syndrome presented with abdominal pain and disseminated intravascular coagulation. Radiographic studies revealed thickening of the gallbladder wall. Following stabilization of the coagulation disorder, the patient underwent a cholecystectomy, and the gallbladder was found to contain Kaposi's sarcoma (KS). There have been no previously published reports of KS found in the gallbladder of a living patient in the absence of cutaneous manifestations of KS. The current case illustrates that KS is a multi-focal systemic disease which may have extracutaneous primary manifestations.

Acquired Immunodeficiency Syndrome↗

Fiber type composition of muscle units in the cat diaphragm.

The fiber type composition of muscle units in the cat diaphragm was examined. As expected, slow-twitch units were composed of type I fibers and fast units were composed of type II fibers. Fast fatigable units were composed of type IIB fibers and fast fatigue resistant units were composed of type IIA fibers. Surprisingly, fast fatigue intermediate units were comprised of both type IIA and IIB fibers.

Adenosine Triphosphatases↗

Oxidative capacity and capillary density of diaphragm motor units.

Motor units in the cat diaphragm (DIA) were isolated in situ by microdissection and stimulation of C5 ventral root filaments. Motor units were classified based on their isometric contractile force responses and fatigue indexes (FI). The muscle fibers belonging to individual units (i.e., the muscle unit) were identified using the glycogen-depletion method. Fibers were classified as type I or II based on histochemical staining for myofibrillar adenosine triphosphatase (ATPase) after alkaline preincubation. The rate of succinate dehydrogenase (SDH) activity of each fiber was determined using a microphotometric procedure. The location of capillaries was determined from muscle cross sections stained for ATPase after acid (pH = 4.2) preincubation. The capillarity of muscle unit fibers was determined by counting the number of capillaries surrounding fibers and by calculating the number of capillaries per fiber area. A significant correlation was found between the fatigue resistance of DIA units and the mean SDH activity of muscle unit fibers. A significant correlation was also observed between DIA unit fatigue resistance and both indexes of muscle unit fiber capillarity. The mean SDH activity and mean capillary density of muscle unit fibers were also correlated. We conclude that DIA motor unit fatigue resistance depends, at least in part, on the oxidative capacity and capillary density of muscle unit fibers.

Adenosine Triphosphatases↗