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Biomedical subjects

J G Gilbert

Publications and source records attributed to J G Gilbert.

29 records · Page 2Linked to original sources
PubMed1976

The place of cytology in laryngeal diagnosis.

A cytological procedure providing useful supplementary information in the diagnosis of laryngeal malignancy is described. Of 51 patients, 22 had complete correlation with histological examination in confirming a benign condition. Twenty patients had complete correlation in confirming a malignant lesion. Five patients showed cellular atypia in the presence of benign conditions. Three showed atypia, of which 2 were malignant, 1 being unstable histologically but with no evidence of frank malignancy. Ten patients had been irradiated previously; in all cases the distinction between residual disease and no evident disease was correctly diagnosed with respect to the histological appearance.

Carcinoma in Situ↗
PubMed1975

Water intoxication after hypophysectomy.

A case of excessive water retention after hypophysectomy is recorded. Its probable cause, inappropriate secretion of ADH, is explained and the diagnosis and management discussed. Three other recorded cases occurring after hypophyseal surgery are mentioned. The importance of postoperative electrolyte measurements in early diagnosis and management is emphasized.

Diuretics↗
PubMedDate not supplied

The DNA sequence and comparative analysis of human chromosome 20.

The finished sequence of human chromosome 20 comprises 59,187,298 base pairs (bp) and represents 99.4% of the euchromatic DNA. A single contig of 26 megabases (Mb) spans the entire short arm, and five contigs separated by gaps totalling 320 kb span the long arm of this metacentric chromosome. An additional 234,339 bp of sequence has been determined within the pericentromeric region of the long arm. We annotated 727 genes and 168 pseudogenes in the sequence. About 64% of these genes have a 5' and a 3' untranslated region and a complete open reading frame. Comparative analysis of the sequence of chromosome 20 to whole-genome shotgun-sequence data of two other vertebrates, the mouse Mus musculus and the puffer fish Tetraodon nigroviridis, provides an independent measure of the efficiency of gene annotation, and indicates that this analysis may account for more than 95% of all coding exons and almost all genes.

Animals↗