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J G Klebe

Publications and source records attributed to J G Klebe.

58 records · Page 4Linked to original sources

Changes in kidney volume during pregnancy in non-diabetic and diabetic rats measured by magnetic resonance imaging.

Consecutive magnetic resonance images were obtained in pregnant animals and their respective controls, and changes in kidney, cortex, medulla, and pelvis volumes were calculated. In non-diabetic pregnant animals, a marked increase in kidney and cortex volumes was observed within the first 15 days of pregnancy (29 and 20%, respectively), while no significant changes were seen in medulla or pelvic volumes. Five days later (near term) and after delivery, kidney and cortex volumes had decreased to values before pregnancy. In pregnant diabetic animals, a 26% increase in renal volume was seen over the first 15 days of pregnancy when compared to the increase seen in non-diabetic pregnant animals. Pregnant diabetic animals had a parallel increase in cortex and medulla volumes, but still no changes in the pelvis volume. In contrast to non-diabetic pregnant animals a non-heterogeneous pattern in renal volume was seen post partum, as not all animals normalized their renal volume.

Animals↗

Ovulation in uremic women: the reproductive cycle in women on chronic hemodialysis.

We studied five uremic women of fertile age and on chronic intermittent haemodialysis over a 3-month period. The purpose of this investigation was to establish how often the hormonal pattern indicated ovulation in uremic women and, thereby, the possibility of an inexpedient pregnancy. The pituitary ovarian axis was estimated by analyzing the serum concentrations of follicle-stimulating hormone, luteotropic hormone, progesterone, estradiol, and prolactin. Forty percent of the investigated cycles seemed to be ovulatory, though with a slightly atypical hormonal pattern. Because of these factors, it is recommended that sexually active women of fertile age and on chronic intermittent hemodialysis consider the use of contraception in order to avoid unwanted pregnancies.

Adolescent↗