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Biomedical subjects

J G Konings

Publications and source records attributed to J G Konings.

15 recordsLinked to original sources
PubMed1993

Functional anatomy of the soft tissues of the hand and wrist: in vivo excursion measurement of the flexor pollicis longus-tendon using MRI.

Magnetic resonance imaging (MRI) of the flexor pollicis longus-tendon (FPL-tendon) with the thumb in different positions allows the in vivo assessment of its abduction-adduction/flexion excursion. Measurements can also be performed in different positions of the wrist. In our study, the mean excursion amplitudes of the FPL-tendon in seven healthy volunteers were 2.6 (+/- 0.26), 2.6 (+/- 0.25), and 2.7 (+/- 0.63) cm for neutral position, ulnar, and radial deviation of the wrist, respectively. The contribution of the abduction-neutral position route and the neutral position-adduction/flexion route to the total excursion of the thumb varied for the different positions of the wrist, despite the equal excursion amplitudes. The possibility of visualization and the accurate determination of the FPL-tendon excursions is of use in the reconstruction and the transposition of the FPL-tendon. In addition, the shift of the FPL-tendon can be visualized for different positions of the thumb and the wrist.

Adult↗
PubMed1992

[Value of proton spin tomography in the diagnosis of intra-articular pathological disorders of the knee].

Magnetic resonance imaging (MRI) of the knee was performed in 50 patients with unilateral knee problems with clinical suspicion of a meniscal tear or degeneration of the cartilage. The findings of the MRI examination were compared with previously performed arthrography and the diagnosis was subsequent confirmed arthroscopically. MRI detected degenerative changes in 69 out of 100 menisci and signs of a meniscal tear in 31 of the menisci. The diagnostic accuracy of MRI for a tear in the medial or the lateral meniscus was 91%. MRI was accurate in the detection of 8/11 ruptures of the anterior cruciate ligament and in 6/13 cases with degenerative changes of the patella.

Adult↗
PubMed1992

[Pyomyositis, not an exclusively tropical disease].

Pyomyositis is considered to be limited to tropical areas. In recent years, however, it is increasingly reported from temperate climate areas, predominantly in immunocompromised patients. Since the disease can mimic several other conditions, it may remain unrecognized for weeks. Two native patients from the Netherlands are presented, neither of them had ever travelled to the tropics. One of the patients had AIDS, the other had no predisposing factors. Pyomyositis can be difficult to diagnose, but in most cases it is easy to cure. Pyomyositis should be considered in the differential diagnosis in patients with fever and localised myalgia.

Abscess↗
PubMed1991

Fusobacterium pyomyositis of the shoulder after tonsillitis. Report of a case of Lemierre's syndrome.

A case of nontropical pyomyositis is reported in a young male without predisposing factors. The disease was preceded by a tonsillitis, and the presentation initially suggested a septic arthritis of the shoulder. Fusobacterium, a highly unusual pathogen in pyomyositis, was isolated from an abscess in the infraspinatus muscle. The increasing frequency of the disease in areas with a temperate climate and the pathogenesis are discussed. Our case had the classic features of Lemierre's syndrome: invasion of the bloodstream by Fusobacterium species from a tonsillitis.

Abscess↗
PubMed1990

[Long-term results of the Swanson prosthesis for the treatment of lunate osteomalacia].

From 1972 to 1982 a silicone implant arthroplasty was performed in 18 patients with Kienböck's disease grade III. In May 1988 all patients had a clinical and radiological re-examination. In the course of time reoperations were performed in 4 patients because of (sub)luxation of the prosthesis. Because of this operation most of the patients had less pain and retained an acceptable function of the wrist. Influence on working circumstances had been considerable in 8 patients. One patient received a disability pension because of this disease. Radiological examination often revealed increased degenerative changes in carpo-radial and intercarpal joints as well as proximal migration of the capitate. There was no clear relationship between residual complaints and function at the follow-up examination and the radiological findings.

Adult↗
PubMed1986

Computed tomography (CT) analysis of the effects of chemonucleolysis.

Computed tomography (CT) was performed on 30 patients with herniated lumbar discs before chemonucleolysis and at three and 12 months postinjection. At three months the compression produced by the herniated disc was reduced in 20 of the 30 patients; at 12 months there was complete relief of compression in all but four patients. Twenty-four patients developed diffuse bulging of the annulus. There was good correlation between the clinical results at three months and the reduction in compression as shown by the CT scan. At 12 months, no correlation was found between the remaining focal abnormalities and the clinical result. None of the patients developed epidural fibrosis. Chemonucleolysis has thus been shown to be an effective treatment of herniated lumbar discs, but it is definitely not indicated in cases where compression of the nerve root or dural sac is due to a bulging annulus.

Adult↗
PubMed1984

The effects of chemonucleolysis as demonstrated by computerised tomography.

Computerised tomography (CT) was performed in 30 patients with herniated lumbar discs; this was done both before chemonucleolysis and three months after. In 20 of the 28 patients who were CT positive, the compression produced by the herniated disc was eliminated or reduced. Twenty-three of the 28 patients developed diffuse bulging of the annulus. There was good correlation between the clinical results at three months and the alteration in compression as shown by the CT scan. No evidence of alteration in the bony relationship was seen in the scan and none of the patients developed epidural fibrosis. Chemonucleolysis has thus been shown to be an effective treatment of herniated lumbar discs, but it is definitely not indicated in cases where compression of the nerve root or dural sac is due to a bulging annulus.

Adult↗
PubMed1983

Analysis of the relationship between the variation in intercleavage times and cell diversification during the cleavage stages of the teleost fish Nothobranchius guentheri.

A cell lineage study up to the ninth cleavage of the annual teleost fish Nothobranchius guentheri is presented and analysed with respect to a possible relationship between cell diversification and intercleavage times. The cleavage pattern contains both regular aspects (formation of the external yolk syncytial layer) and irregular aspects (formation of the deep cells and the enveloping layer cells). Cells that generate cells which divide again have a similar intercleavage time independent of the cell type of their daughters. Peripheral blastomeres with a shorter intercleavage time, that are situated near the centre of the blastoderm, contribute more to the formation of the deep cell population than those blastomeres with a longer intercleavage time, that lie closer to the margin of the blastoderm. No evidence was found for a relationship between the duration of the cell cycle and the cell type(s) a cell generates, nor for the involvement of mitotic gradients in cell diversification.

Animals↗
PubMed1983

Analysis of the variability and of the lengthening of intercleavage times during the cleavage stages of Nothobranchius guentheri.

By means of time-lapse cinematography the early development of the annual fish Nothobranchius guentheri was recorded on 16-mm film up to the tenth cleavage round. Analysis of the films showed that the mean intercleavage time is much the same up to the seventh cleavage. Thereafter, intercleavage times increase, with steps of about 30 min or a multiple of it, at each subsequent cleavage. As development proceeds, the variability in intercleavage times increases. A positive correlation of sister intercleavage times exists from the seventh generation, whereas intercleavage times of mother-daughter cells are positively correlated in the ninth generation. The results suggest that the lengthening of the cell cycle after the seventh cleavage is due to the insertion of a time period in a programmable mitotic clock. The duration of this time period differs between the different cell lines of a pedigree, probably because of a difference in cell volume. Variability in intercleavage times might also arise as a result of some random transition which the cells traverse only once per 5 min with a transition probability of 0.67/5 min.

Animals↗