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Biomedical subjects

J G Spector

Publications and source records attributed to J G Spector.

32 records · Page 2Linked to original sources
PubMed1990

Surgical therapy of the eyelids in patients with facial paralysis.

Patients with facial paralysis have a degree of lagophthalmos and paralytic ectropion. We present our experience in the surgical management of 25 consecutive patients treated for these problems. Paralytic lagophthalmos was corrected using gold weights inserted into the upper eyelid. The advantages and disadvantages of this surgical technique are reviewed. Medial canthoplasty and lateral canthoplasty were performed to rectify paralytic ectropion. Ancillary procedures included browpexy, upper-lid blepharoplasty, and temporalis sling. The results were excellent in 23 of 25 patients and good in the remaining two. After a minimum of 6 months' follow-up, there were no complications. The authors believe that the above procedures will yield consistently excellent cosmetic and functional results in patients with paralysis of the eyelids.

Cranial Nerve Neoplasms↗
PubMed1990

Clinical classification and staging for primary malignancies of the maxillary antrum.

A study of 51 patients with primary malignant maxillary sinus neoplasms was conducted. None of the patients had neck nodes and/or metastases, and each had 5-year follow-up. The tumors were staged according to the 1983 and 1988 American Joint Committee on Cancer staging systems for maxillary sinus cancers. There were 13 early stage (T1, T2) and 38 advanced (T3, T4) tumors in both systems. Cox regression analyses of survival curves showed increasingly worse prognoses for advanced tumors in both T-staging systems. Further analyses showed a significant difference in survival between T3 and T4 in the 1988, but not in the 1983 system. There were no significant differences in survival according to treatment modality or histological type of malignancy. We conclude that the 1988 system prognosticates successfully for T-stage (1 to 4) and demonstrates significant improvement in detecting T3 versus T4 differences compared to the 1983 system. The 1988 system applies equally for epidermoid cancer and other malignancies of the antrum.

Adult↗
PubMed1989

Long-term follow-up and recent observations on 305 cases of orbital decompression for dysthyroid orbitopathy.

Dysthyroid exophthalmopathy (orbitopathy) results from an enlargement of extraglobal orbital structures, producing ocular proptosis, optic nerve compression, and corneal exposure. Treatment with corticosteroids and radiation may be beneficial; refractory cases require surgical decompression of the orbit. Transantral orbital decompression was described by Walsh and Ogura and has been performed in over 350 patients at this institution. A review of 305 patients with long-term follow-up was performed. Visual acuity improved or was maintained at preoperative levels in over 95% of the patients, with ocular recession ranging from 1 to 12 mm (average: 4 mm). Postoperative ocular balance of relative exophthalmos was to within 1 mm in 76% of the patients and to within 2 mm in approximately 90% of the patients. Normal postoperative extraocular muscle balance was present in 99 patients. Immediate postoperative diplopia was noted in 206 patients. Long-term follow-up revealed that in 137 of these patients, diplopia resolved or responded to conservative management. Extraocular muscle surgery was required for correction in 69 patients. Twenty-seven patients had postoperative complications. These included 16 patients with hypesthesia of the infraorbital nerve, 5 patients with sinusitis, 3 patients who had incomplete decompression, 2 patients with oral antral fistulae, and 1 patient who had CSF rhinorrhea. Five patients, despite surgery, radiation, and steroid therapy progressed to blindness. We conclude that this procedure is effective and carries few complications. Orbital imaging, using computed tomography or magnetic resonance sequence with reconstructive capabilities, permits early diagnosis and treatment of dysthyroid compression optic neuropathy.

Adolescent↗
PubMed1989

Preoperative assessment of parotid masses: a comparative evaluation of radiologic techniques to histopathologic diagnosis.

A double-blind, retrospective analysis of 110 sequentially operated parotid masses compared the usefulness of preoperative radiologic evaluation to histopathologic diagnosis. The radiologic assessment included 25 sialograms, 162 computed tomography scans, and 10 nuclear magnetic resonance images. The diagnosis is influenced by the following four parameters of computed tomography: tumor borders, density, homogeneity, and enhancement. Well-defined borders, a homogeneous appearance, and high density strongly favor the diagnosis of a benign tumor or a low-grade malignancy (96.7%). Ill-defined tumor borders, heterogeneity, and high density indicate mainly a high-grade or recurrent malignancy (68.8%). Ill-defined borders, a heterogeneous appearance, and mixed density identify a lymphoepithelial lesion, lymphangioma, or sialoadenitis (100%). Sialography is cost effective in the evaluation of lymphoepithelial lesions. Computed tomography sialography offers no advantages over computed tomography with intravenous contrast. High-resolution computed tomography with intravenous contrast is highly sensitive for tumor detection (97%). Magnetic resonance imaging is complementary or superior to computed tomography (100%).

Clinical Trials as Topic↗
PubMed1988

Parotid masses: evaluation, analysis, and current management.

Two hundred thirty-one sequential parotid masses seen from January 1982 to July 1986 were reviewed for their clinical presentation, diagnostic evaluation, pathologic findings, and therapeutic approach. The results were compared with the previously reported findings on parotid masses. There were 146 (63.2%) benign tumors, 50 (21.6%) malignancies, and 35 (15.2%) nonmalignant lesions. Tumors were classified according to their histopathologic diagnosis. An asymptomatic mass was the most common presentation. Radiological evaluation was mainly with computed tomography. The primary surgical procedure was parotidectomy with facial nerve preservation. A selected group of patients was referred for radiation therapy. Our study demonstrated that non-neoplastic lesions contribute a significant number of masses in the differential diagnosis of parotid tumors. Metastatic squamous cell carcinoma was the most frequently encountered malignancy. Deep lobe tumors were twice as common as previously reported.

Adolescent↗
PubMed1988

Management of juvenile angiofibromata.

Twenty-eight angiofibromata, treated between 1971 and 1988, were reviewed according to their patterns of invasion, blood supply, treatment modality, and clinical course. All patients were males, and two patients were black. The average age was 14.8 years. Nasopharyngeal masses, epistaxis, and facial asymmetry were the most common presenting symptoms. Tumors extended along predetermined pathways following the vascularity of the external carotid system. CNS extension arose via the superior orbital fissure or direct extension from the sphenoid sinus. Angiography described the neoplastic vascularity, CT with contrast demonstrated tumor location and extracranial extension, and MRI best demonstrated CNS invasion. All lesions were reclassified according to the American Joint Committee staging system. Twenty-seven patients were operated upon; four with cryotherapy and 23 following embolization. Two tumors recurred and needed additional surgery. One patient with CNS invasion was treated with estrogen and radiotherapy for cure. Tumor staging is not particularly helpful in decision making, because surgery must be individualized according to tumor location and extent. Surgical approaches for specific tumor locations are discussed.

Adolescent↗
PubMed1987

Mimetic surgery for the paralyzed face. Neural and plastic procedures.

One hundred and thirty-eight patients with facial nerve paralyses were treated by various surgical methods. One hundred and six patients had total facial nerve paralyses and thirty-two had segmental paralyses. In the total paralysis group, 80 patients had oncologic procedures or tumor induced paralysis. In the segmental paralysis group, 21 patients had malignancies. Two patients had idiopathic facial nerve paralysis. In the total paralysis group, 75 had neural reconstructions, 7 neuromuscular pedicles and 26 muscle-fascia transpositions. The segmental paralysis group was divided into an upper facial palsy group (N = 14) and lower facial palsy group (N = 18). Twelve patients had neural transpositions, six had muscle-fascia transpositions and 16 had plastic reconstructions. The results were analyzed by various methods and grading systems. The data indicates that neural repairs produce better results than muscle-fascia transpositions or plastic reconstructions. Within the repairs, the procedures are listed in an hierarchical order of cosmetic and functional results. The average follow-up for the entire group is 3.4 years. The average follow-up for the neural repair group is 3.6 years, and for the muscle fascia transpositions is 14.4 months.

Adolescent↗
PubMed1987

Allergic Aspergillus sinusitis: concepts in diagnosis and treatment of a new clinical entity.

The clinical features in 15 young adult patients with allergic Aspergillus sinusitis includes a history of asthma, recurrent nasal polyps, and radiographic evidence of pansinusitis. Multiple surgical procedures were performed on 12 patients. The histologic diagnosis is made on the mucinous material which contains eosinophils, fungal hyphae (Aspergillus species), and Charcot-Leyden crystals. Mycetomas, direct mucosal and soft tissue invasion by fungi, were not observed. Immunologic findings include an immediate cutaneous reactivity to Aspergillus in 60% of patients, total serum IgE elevation in 85%, and serum precipitins to Aspergillus in 85%. A new therapeutic protocol was devised based on the current treatment of allergic bronchopulmonary aspergillosis. Therapy includes wide local debridement, adequate sinus aeration, and the postoperative use of systemic steroids. Seven patients placed on systemic corticosteroids are asymptomatic for a mean of 14 months. Diagnosis of allergic Aspergillus sinusitis requires a high index of suspicion, a confirmatory diagnosis from the inspissated mucus, and an immunologic evaluation prior to the institution of corticosteroid therapy.

Adolescent↗
PubMed1985

Facial nerve palsy associated with Warthin's tumor.

A solid parotid mass and an ipsilateral facial weakness is nearly pathognomonic for a malignant parotid neoplasm. There are only a few documented cases in the world's literature of nonmalignant parotid lesions causing facial paralysis. A case is presented of a Warthin's tumor causing a facial palsy. Extensive areas of necrosis, inflammation, and fibrosis surrounding branches of the facial nerve may have accounted for the facial palsy.

Adenolymphoma↗
PubMed1985

Surgical management of cutaneous carcinomas at the inner canthus.

Surgical management of carcinomas at the inner canthus is based on three criteria which are listed in a descending order of importance: tumor resectability with adequate margins, preservation of vision, and acceptable cosmetic result. The lesions resected are to create trapezoid or rectangular defects which can be closed simply with primary closures or with Z- or W-plasties. In medium sized defects skin is borrowed from the glabella, upper nasal dorsum, or nasolabial sulci and used as rotational flaps. In more extensive lesions, through and through defects, or when lined flaps are required, nondelayed midline forehead pedicled or island flaps are employed. For very large defects, sliding cheek flaps, sickle forehead flaps, horizontal forehead flaps, and (in rare instances) scalping flaps where the distal segment is the temporal, hairless skin is used. Tumors which extend intracranially and are deemed resectable are removed with a combined intracranial approach. The latter may be via a transfrontal sinus resection or a combined lateral rhinotomy and frontal craniotomy resection. Regional lymph node metastasis normally requires a superficial parotidectomy, radical neck dissection (including submaxillary, angular, and mandibular nodes), and occasionally postauricular lymph node dissection. Distant metastases are contraindications for major surgical procedures.

Carcinoma↗
PubMed1985

Mimetic surgery for the paralyzed face.

One hundred ten patients with facial nerve paralyses were treated by various surgical methods. Eighty-six patients had total facial nerve paralyses and 24 had segmental paralyses. In the total paralysis group, 62 patients had oncologic procedures or tumor induced paralysis. In the segmental paralysis group, 14 patients had malignancies. Two patients had idiopathic facial nerve paralysis. In the total paralysis group, 59 had neural reconstructions, 7 neuromuscular pedicles, and 20 muscle-fascia transpositions. The segmental paralysis group was divided into an upper facial palsy group (n = 11) and lower facial palsy group (n = 13). Five patients had neural transpositions, 5 had muscle-fascia transpositions, and 14 had plastic reconstructions. The results were analyzed by various methods and grading systems. The data indicate that neural repairs produce better results than muscle-fascia transpositions or plastic reconstructions. Within the repairs, the procedures are listed in an hierarchical order of cosmetic and functional results. The average follow-up for the entire group was 2.8 years. The average follow-up for the neural repair group was 3.2 years, and for the muscle fascia transpositions, 14.1 months.

Action Potentials↗
PubMedDate not supplied

Traumatic perforation of the pyriform sinus: CT demonstration.

Hypopharyngeal perforation secondary to tracheal intubation is a rare and serious complication. Radiographic evaluation is helpful when the clinical diagnosis is not obvious. In one such case CT demonstrated the site of perforation and its extension into the superior mediastinum, facilitating the subsequent surgical approach.

Adult↗