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Biomedical subjects

J Géraud

Publications and source records attributed to J Géraud.

At least 19 recordsLinked to original sources

[Peripheral neuropathy with cryoglobulinemia (author's transl)].

The author describe 2 personal observations of peripheral neuropathy with cryoglobulinemia and the 28 cases previously recorded are reviewed. The characteristics of the usually sensorimotor neuropathy are not specific. Nevertheless, the association with purpura, Raynaud's syndrome and leg ulcers and the inconstant aggravation of the symptoms with cold allow the diagnosis to be suspected on clinical grounds. Cryoglobulin can be recognised by immunoelectrophoresis and classified as type I monoclonal, types II and III mixed and polyclonal. Associated disease should be looked for; lymphocytic proliferation or auto-immune disease. If none is found a diagnosis of essential cryoglobulinemia can be made but with caution as cryoglobulinemia can precede by several years the appearance of associated disease.

Aged↗

[Pseudo-tumoral softening of the cerebellum].

The author establish an onerall picture of cerebellar infarction with brain stem compression after reviewing 63 cases published in the literature and 4 personal observations. The frequency of this affection can be compared with that of cerebellar hematomas. Diagnosis is based on its predominance in males, the early age at which it appears, its rapid and typical onset, and the delayed signs of brain stem compression. Conventional neuroradiological procedures show an expanded cerebellar volume, and the scanner can specify the ischaemic nature of the lesion. As soon as changes in consciousness occur surgical decompression is necessary, first by external drainage of C.S.F. and later, if necessary, by direct access to the postdrior fossa.

Adult↗

[Benign intracranial hypertension due to thrombosis of a transverse sinus. Diagnosis by scintigraphy using bleomycin labelled with cobalt 57 (author's transl)].

In a case of benign intracranial hypertension with no apparent aetiology, cerebral scintigraphy demonstrated abnormal uptake in the left transverse sinus 24 hours after injection of the isotope. This sinus was seen to be thrombosed by cerebral angiography. On the basis of this case, the role of cerebral venous thrombosis in cases of "pseudo-tumor cerebri" is discussed.

Adult↗