Biomedical subjects
Publications and source records attributed to J García Herruzo.
A young drug addict with positive anti-HIV antibodies, OKT4/OKT8 ratio below 1, oropharingeal candidiasis and pulmonary Pneumocystis carinii infection, dies due to a cerebral abscess with a septic status. The postmortem microbiologic study shows pulmonary abscesses and Nocardia asteroides is isolated from lung tissue and spinal fluid. We note out the rareness of this pathology and its relation to AIDS.
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The incidence of shigellosis at the Residencia Sanitaria Fernando Zamacola (Cáciz, Spain) and the antibiotic sensitivity of 94 strains of Shigella sonnei and 40 strains of Shigella flexneri, isolated during the year 1979, has been studied taking into account the present status of strain resistance to the major antibiotics. Three epidemic bouts of shigellosis were detected: one in february by Shigella sonnei (16 cases), and two others in august-september and november due to Shigella flexneri (43 and 29 cases). Children 2 to 5 years old had the highest incidence of Shigella infection. Almost all strains isolated were resistant to the sulphonamides (99.77%). Ampicillin and chloramphenicol had little efficacy against Shigella flexneri (95.00 and 92.50% resistance). The percent resistance of Shigella sonnei strains to phosphomycin was elevated (44.69%). All strains studied were sensitive to colimycin and showed little resistance to the combination trimethoprim-sulfamethoxazol (16.42%).
An epidemic outbreak, caused by "Shigella sonnei" in a kindergarten, affecting a high percentage of children aged two to seven years is described. On searching into the sensitivity is isolated strains to a wide range of antibiotics, it was observed that all them showed resistance to sulphonamides and a 57.19% were also resistant to phosphomycin. After doing the pertinent investigations and epidemiological analysis possible mechanisms of illness, transmission and dissemination are studied, evaluating the clinical symptoms that these children showed as well as the clinical course after treatment with ampicillin.
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