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J Gayà

Publications and source records attributed to J Gayà.

14 recordsLinked to original sources
PubMed2006

[Implantation of a hospital registry of hereditary nonpolyposis colorectal cancer].

INTRODUCTION: Identification of patients with hereditary nonpolyposis colorectal cancer (HNPCC) can allow colorectal cancer (CRC) prevention through colonoscopy and polypectomies. The purpose of this study was to report the clinical characteristics of HNPCC families in our registry. PATIENTS AND METHOD: HNPCC was identified using the Amsterdam criteria. Familial clustering of CRC and extracolonic cancers were investigated in families. Individuals at risk were offered annual colonoscopy, starting from the age of 25 years. RESULTS: Twelve HNPCC families were identified. There were 46 cases of CRC in 38 patients. The mean age at diagnosis of CRC was 45.4 +/- 12.7 years (range 25-73 years). In patients with documented disease, right-sided tumors predominated. Eleven patients with extracolonic cancer were identified (six tumors located in the endometrium). Of 43 at-risk individuals, 29 accepted surveillance. CONCLUSIONS: Our data confirm the importance of the family history in identifying HNPCC. This study confirms previously described characteristics in HNPCC, namely, early age at onset of CRC, right-sided predominance, multiple synchronous and metachronous neoplasms, and increased extracolonic cancers. This is the first study of clinical data in a Spanish HNPCC registry.

Adult↗
PubMed1998

Combined percutaneous-endoscopic pancreatic pseudocyst drainage--a new technique.

Surgical drainage has been the traditional approach to treating pancreatic pseudocysts. Percutaneous and endoscopic treatment of pancreatic pseudocyst were recently suggested as an alternative to surgery. In order to avoid the difficulties that can be observed in some patients in the percutaneous or endoscopic management of pancreatic pseudocysts we have used a combined procedure. We have treated by the "rendezvous" technique two patients suffering from pancreatic fistula complicating pancreatic pseudocysts. A percutaneous-endoscopic approach was used to place an internal stent between the pseudocyst and the duodenum. We have applied the same combined approach to the main pancreatic duct that is usual for bile duct obstruction without noticeable complications. Although application of this technique will be very limited, we advocate in the future the combined approach to treating pancreatic pseudocyst when there is a fistula between the fluid collection and pancreatic duct, and the downstream main pancreatic duct is obstructed, preventing use of the transpapillary approach.

Adult↗
PubMed1998

[Celiac disease of the adult following orthotopic liver transplantation. Description of a case].

A case of celiac disease of the adult is herein described in a patient with a history of orthotopic liver transplantation because of cirrhosis due to hepatitis C virus. The patient presented with a decrease in the levels of cyclosporinemia, diarrhea and an increase in transaminases. This is an infrequent form of presentation leading to differential diagnosis with a complication related to the liver disease.

Celiac Disease↗
PubMed1997

[Prevalence of monosymptomatic celiac disease in patients with iron deficiency anemia].

A prospective study of the prevalence of monosymptomatic celiac disease presented as ferropenic anemia in patients admitted for study such complication of was carried out. All the patients were evaluated by gastroscopy and biopsy of the distal duodenal segment, regardless of endoscopic appearance. Patients presenting an endoscopic lesion clearly suggestive as the origin of the chronic bleeding were excluded from the study. The prevalence of celiac disease, the only manifestation of which was ferropenic anemia, was 3.3% in this series. What is important to note in this study is the importance of duodenal biopsy in the study of ferropenic anemia, with the aim of avoiding diagnostic delay of a possible monosymptomatic celiac disease as the cause of the anemia.

Adult↗
PubMed1987

Endoscopic diagnosis of the excluded gastric antrum.

A 69-year-old woman was admitted to our hospital with GI haemorrhage. Twenty-two years previously, she had had a Billroth II operation to treat a duodenal ulcer. A gastroscopy performed on admission showed two ulcers on the anastomotic crest. We were able to visualize all of the blind duodenal pouch and how in the proximal end the mucosa was prominent and different in colour. Excluded gastric antrum was confirmed by endoscopic biopsy. We discuss the different approaches to the diagnosis of excluded gastric antrum, and we conclude that endoscopy must play important role in the diagnosis of this pathology.

Aged↗
PubMedDate not supplied

[Osteomatous jaw lesions in familial adenomatous polyposis].

The first aim of this study is to assess the frequency of osteomatous jaw lesions in patients with a diagnosis of familial adenomatous polyposis (FAP), and a group of FAP-relatives from the FAP registry of Majorca (Balearic Islands, Spain). The second aim is to study the predictive significance of osteomatous jaw lesions in families with FAP. The study included forty-two people. Twenty-five patients and seventeen relatives. All individuals underwent pantomography. Osteomatous jaw lesions were diagnosed in 68% of FAP-patients, and 6% of FAP-relatives. The difference was statistically significant (p < 0.001). The sensitivity was 68%, the specificity 94% and positive predictive value 94%. This frequency of osteomatous jaw lesions agree with previous studies of FAP-patients (57-82%), but differ from these of the previous studies of FAP-relatives (16-18%). The available method detect APC (adenomatous polyposis coli) gene mutations in 48-82% of FAP families. In the families without detected mutation, non-informative study or non-available study, the screening is based in seriated sigmoidoscopy and study of the extraintestinals lesions of the FAP syndrome. The frequency of osteomatous jaw lesions in FAP-patients is greater than the observed in FAP-relatives (p < 0.001). Osteomas in families with FAP are of predictive significance.

Adenomatous Polyposis Coli↗
PubMedDate not supplied

[Endoscopic management of foreign bodies in the esophagus. Results of a retrospective series of 501 cases].

We present the results of a retrospective study of endoscopic management (with flexible endoscopy) in 501 patients admitted for suspected ingestion of a foreign body between 1977 and 1997. The mean age of the patients was 55.73 19.38. Foreign bodies were found in the esophagus in 322 patients (64.3%) and endoscopic removal was successful in 307 (95.35%). More experienced endoscopists, with more than 45 cases, had a higher success rate (98.1%) than did less experienced endoscopists (87.9%) (p < 0.01). The most frequent type of foreign body in our series was meat bolus (32.8%). Underlying disease was found in 38.9%, and peptic stenosis was the most frequent. The only severe complication found was esophageal perforation in one patient (0.3%). Emergency flexible endoscopy is the most effective method for managing patients admitted for suspected ingestion of a foreign body and for the removal of foreign bodies located in the esophagus.

Adult↗