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Biomedical subjects

J Giron

Publications and source records attributed to J Giron.

At least 19 recordsLinked to original sources

Chest radiography and high resolution computed tomography of the lungs in asthma.

CT scans have been studied only in asthmatics who were smokers, and no such study has been performed in patients with chronic uncomplicated asthma where a permanent bronchial destruction is likely to occur after a long course of the disease. The object of the study was to characterize CT-scan abnormalities and determine whether bronchial destructive lesions may be observed. Fifty-seven adults with chronic asthma of variable severity and etiology and 10 normal subjects were studied. None of the subjects smoked. Chest radiographs and HR-CT scans were performed in all patients. To discriminate between reversible and irreversible CT-scan abnormalities, two examinations were made in 10 patients with acute asthma both before and 2 wk after parenteral high dose corticosteroid treatment. The chest radiographs showed the expected abnormalities of asthma in 37.8% of the asthmatics. CT scans were abnormal in 71.9% of the asthmatics. Reversible abnormalities included mucoid impactions, acinar pattern, and lobar collapse. Irreversible abnormalities included bronchiectasis, bronchial wall-thickening, sequellar line shadows, and emphysema. Most of these abnormalities are likely to be related to bronchial destruction.

Adult

[Cervico-mediastinal cystic lymphangioma].

Anterior cervico-mediastinal tumors in children, especially if they are cystic, often correspond to the diagnosis of cystic hemolymphangioma. CT and Chest US are contributive for the diagnosis and the pre-operative staging.

Adolescent

[Primary mediastinal myxoid liposarcoma. Apropos of a case].

Liposarcoma is an uncommon mediastinal tumor provides limited CT histologic date. The prognosis depends on the histological grade and surgical possibilities. The authors report a case of mediastinal liposarcoma and discuss the correlation between imaging findings, outcome and histological status.

Humans

[Lung metastasis].

Pulmonary metastasis of non small cell lung carcinomas are commonly nodular. The isolated nodular form must be diagnosed from double location carcinomas. The lymphangitic carcinomatosis semiology is best demonstrated with HR-CT-Technic. Endobronchic, alveolar and multi-micro angiopathy with emboli are less common.

Carcinoma, Non-Small-Cell Lung

[An unusual miliary pattern].

Syndromes presenting with interstitial radiological signs are often difficult to diagnose aetiologically. Surgical biopsy prevents certain rare cases being neglected notably when there are atypical manifestations. We describe a case of bronchiolitis obliterans with an organising pneumonia which was classical as regards the histology and its response to treatment but unusual as regards the clinical presentation and the aetiology.

Adult

[Pleural involvements in thymoma. Apropos of 5 cases and review of the literature].

The authors report five cases of pleural involvement in patients with thymoma. In 3 cases these sites were not directly related to the primary and in 1 case they constituted the first event in the disease. CT and MRI allow effective assessment of these pleural lesions ... provided this phenomenon, reported in the literature, is well known by the radiologist.

Adult

[Magnetic resonance imaging in the bone sites of malignant non-Hodgkin's lymphoma. Apropos of 16 cases].

The primordial role of MRI in the staging of primary or secondary bone tumors has been clearly established. The authors report a study of 16 patients with NHL with suspected bone involvement, investigated by conventional radiography, bone scan, CT, bone marrow biopsy and MRI. The authors believe that, in the future, MRI will have an important role in the staging and follow-up of treatment of bone lymphomas. Better than any other techniques, MRI provides a precise assessment of tumor extension. It also represents a valuable method for monitoring patients during treatment by visualising the course of the disease.

Adult

[Bronchiolitis obliterans with pneumonic organization. Apropos of a case and review of the literature].

The authors report a case of bronchiolitis obliterans with organizing pneumonia (BOOP) pathologically proved. They give an analysis of the radiological semiologic findings on plain-film and high-resolution CT (HR-CT). In 1985, Epler proposed a nosologic status but the review of the literature and the findings of their own case give to the authors, the opportunity to discuss the entity on the clinical, evolutive, radiological and pathological point of view.

Bronchiolitis Obliterans

[Role of x-ray computed tomography in the preoperative evaluation of aneurysm of the abdominal aorta].

The authors have studied the files of 50 consecutive patients (1987-89) operated for abdominal aortic aneurysm (AAA) and examined with CT. The criteria for inclusion were surgical features. CT can be made more accurate for the study of AAA: Thus the location of the neck of the aneurysm relative to the renal arteries was defined in 94% of all cases. In addition, CT yields information about the wall of the aneurysm, whether it be thickened (3 inflammatory aneurysms were properly diagnosed) or, mor importantly, weakened (solution of continuity in the wall in the "prior-to-rupture" appearance). Owing to the quality of its performances and to its noninvasive character, the authors regard CT with contrast injection as an essential technique for the preoperative assessment of abdominal aortic aneurysm in most cases. The examination must be carried out strictly, especially for the contiguous sections of the renal arteries and their extension to the crural arch. As it demonstrates weakened areas more easily, a more accurate study of the aneurysmal wall with CT might increase the surgical indications for some smaller aneurysms, the potential evolution of which does not seem to be associated with their diameter only.

Aged

[Role of modern imaging (CT-MRI) in the preoperative evaluation of bronchial cancers. Results in 202 cases].

The authors present the results of a comparative prospective study of the staging 202 bronchogenic carcinomas (T and N) before surgery. The results of CT (202 cases) and MRI (64 cases) were compared with surgical evaluation and pathologic findings. CT and MRI were part of the decisive criteria for therapeutic-surgery choice and were interpreted before surgery. The results showed poor sensitivity for the T and N but better specificity. MRI is superior to CT with the 3 dimensional demonstration and T1 T2 weighted sequences, but its utility remains limited. The authors give their preferred indications for MRI investigation after CT staging. Staging by CT (and MRI) is of great value to avoid impossible thoracotomy and to confirm the findings of mediastinoscopy (suspected N2 and even more N3).

Adult

[Magnetic resonance imaging of the larynx. Its contribution compared to x-ray computed tomography in the pre-therapeutic evaluation of cancers of the larynx. Apropos of 90 surgical cases].

The authors report a prospective and comparative study of the pre-operative staging of 90 laryngeal carcinomas by CT and MRI, with blind analysis of each examination. The radio-anatomic correlations and the inter-method correlations (CT versus MRI) are reported. According to the authors MRI seems to be the method of choice because of its capabilities in soft tissues differentiation and because of its multiplanar representation. The motion artefacts are resolved by the fast imaging technique and the spatial resolution is optimized by special surface coils.

Epiglottis