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Biomedical subjects

J Glaninger

Publications and source records attributed to J Glaninger.

At least 19 recordsLinked to original sources

[Laryngeal and hypopharyngeal carcinoma--the limits and advantages of sonography].

29 patients with carcinoma of the larynx and the hypopharynx were evaluated not only for staging cervical lymph nodes but also for classification of the primary tumour. With appropriate technique it is possible to assess tumour infiltration (T4) of surrounding tissue of the larynx at all levels. Tumour classification T1 to T3 is possible in patients with tumour of the epiglottis (regio supraglottis, UICC). The endolaryngeal tumour T1 to T3 (regio glottis and subglottis, UICC) still remains the domain of the microlaryngoscopy. The limits of the method are apparent in hypopharynx carcinomas where in only 50% of the patients the tumour could be assessed.

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[Sudden deafness in old age].

The sudden hearing impairment sensu stricture constitutes an otologic emergency, the genesis of which is still a mystery. The one-sided, reduced auditory sensitivity (labyrinthine deafness, sensorineural lesion) occurs unexpectedly and, more often than not, in good general condition with the remaining otologic diagnosis showing almost no anomalies. The cause for this impairment is considered to be a cochlear malfunctioning of the microcirculation with ensuing hypoxia/anoxia in stria vascularis and in Corti's organ, which is caused by a change in the circulation qualities of the blood (hemagglutination, aggregation of thrombocytes etc.) sometimes in the wake of a viral infection. Although sometimes spontaneous remissions of the sense of hearing occur in subjects suffering from a sudden hearing impairment - with no prognostic parameter, however - it is of utmost importance to start therapy immediately after the first symptoms have occurred. Therapeutic measures should aim at a reactivation of the impaired microcirculation in order to eliminate the lack of oxygen in the areas concerned. In addition to the indispensable internal treatment, it is recommended to use dextran of low molecular weight to attain hemodilution as well as aggregation inhibitors to improve the rheologic qualities of the blood.

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[A meaningful antibiotic therapy of diseases of the ear, nose and throat in old age (author's transl)].

Each stage of life is characterized by the prevalence of certain affections; among others, inflammatory diseases of the ear, nose and throat are frequent in old age. Therefore, specific problems of chemotherapy in old age are dealt with in general terms in the introduction, with special stress being placed on the functions of individual organs, mainly of the kidneys, and on questions of disturbed absorption. Inflammations caused by streptococci, requiring at least ten days of antibiotic treatment, always deserve particular attention, and so do staphyloccocal diseases, requiring the selective administration of semi-synthetic pencillines (sioxazol preparations). Penicillin is still the first choice among all antibiotics, penicillin substitutes, to be used in case of allergies, are listed according to their order of value. As anaerobic germs may also be present in the ENT area, the effective modern therapy by means of special antibiotics is also referred to. Finally, due consideration is given to local antibiotic therapy, with an emphasis on the ototoxicity of chemotherapeutical agents, such as amino-glycosides.

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