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Biomedical subjects

J Goich

Publications and source records attributed to J Goich.

16 recordsLinked to original sources
PubMed1995

[Cardiovascular diseases secondary to active and passive smoking].

This articles reviews the effects of smoking on the cardiovascular system. Smoking accelerates and aggravates atherosclerosis and increases the risk of coronary artery disease and its clinical manifestations (unstable angina, acute myocardial infarction and sudden death), cerebrovascular diseases, aortic aneurysms and peripheral artery occlusive diseases. Smoking is considered the most important modifiable risk factor for these diseases. Fortunately, quitting smoking reduces and even normalizes cardiovascular risk.

Aortic Aneurysm↗
PubMed1989

[Efficacy of propafenone in supraventricular arrhythmias].

We evaluated the results of intravenous administration of propafenone in 44 patients with rapid symptomatic supraventricular arrhythmia of less than 1 month duration. Mean age was 54 years and 22 were females. Propafenone, 2 mg/kg was given over 15 min and blood pressure and heart rate were monitored in the following hour. Sixteen out of 19 (84%) episodes of paroxysmal supraventricular tachycardia in 15 patients reverted to sinus rhythm at a mean interval of 11 min. None of 14 patients with atrial flutter reverted to sinus rhythm, but the ventricular rate decreased from 143 +/- 38 to 110 +/- 41 (p less than 0.02). The mechanism involved was slowing of the atrial cycle with associated increase A-V block in 7 patients. One patient experienced 1:1 conduction at a rate of 214 per min. Twenty seven % of 15 patients with atrial fibrillation reverted to sinus rhythm; ventricular rate decreased from 134 +/- 40 to 98 +/- 22 (p less than 0.05) in the remaining cases. There were no significant side effects of the drug and systolic blood pressure decreased from 109 +/- 27 to 99 +/- 30 beats per min (p less than 0.05) with no change in diastolic pressure.

Adult↗
PubMed1989

[Constrictive pericarditis: diagnostic aspects and surgical results in 23 cases].

We reviewed the clinical data on 23 patients operated on for constrictive pericarditis. Mean age was 35 years and 17 were males. The chief complaint was dyspnea (87%). Outstanding physical findings were venous hypertension (96%), hepatomegaly (78%), ascitis (57%), pulsus paradoxus (57%) and Kussmaul sign (43%). The ECG, although always abnormal was non contributory. Chest X ray findings included cardiomegaly (48%) and pericardial calcification (35%). Half of the cases showed pericardial thickening and abnormal septal motion on M mode echocardiography. An equalization of diastolic pressures and the dip and plateau sign was confirmed at cardiac catheterization in all cases. The etiology could be established in only 6 patients (tuberculosis 3, traumatic 2 and septic 1). Surgical mortality was 9% (2 patients). Follow up was available on 10 patients at a mean of 35 months, 9 in functional class I and 1 in FC II.

Adolescent↗
PubMed1976

Effect of heart rate on regional coronary blood flow.

The effect of tachycardia on the distribution of coronary blood flow was studied in the dog using the radioactive microsphere technique. Increasing heart rate from 1.7 to 3.0 Hz produced an increment of flow to the inner and outer layer of both ventricular walls. However, the flow ratio, inner layer to outer layer, increased in the right ventricular wall and decreased in the left wall. Measurements performed in ventricular regions with previous vasodilatation and during right ventricular hypertension revealed that the comparatively larger vasodilatation reserve of the right ventricular subendocardium is due to the lower pressure this ventricle develops normally.

Animals↗