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Biomedical subjects

J González Tuero

Publications and source records attributed to J González Tuero.

14 recordsLinked to original sources

[Fibroepithelial polyp of the urethra in an adult].

We present the case of a fibroepithelial polyp of the prostatic urethra in a forty-five year old patient. This type of polyp is rare in the adult. The principal symptoms which the patient presented were haematuria and an intermittent reduction in micturitional flow. Endoscopic images of the tumour are shown and certain details of its histology; this is a polypoid lesion of loose connective tissue covered by typical urothelium, with occasional fascicles of smooth muscle, no prostatic-type glandular structures and no appreciable inflammatory component.

Cystoscopy↗

[Non-functional renal paraganglioma associated with carotid paraganglioma and appendicular mucocele].

OBJECTIVE: A case of nonfunctional renal paraganglioma associated with appendicular mucocele and metachronic carotid paraganglioma is presented. METHODS/RESULTS: A 68-year-old patient consulted for abdominal pain. Patient evaluation with US, CT and opague enema showed an elongated mass that compromised the cecum and a solid mass in the right kidney. The patient underwent appendectomy and radical right nephrectomy. The anatomopathological findings showed an appendicular mucocele and renal paraganglioma. The postoperative hormone analyses were normal. A carotid paraganglioma was removed 8 months later. CONCLUSIONS: Renal tumors arising from neural crest cells are uncommon. To our knowledge, this is the third case of nonfunctional renal paraganglioma reported in the literature. The associated appendicular mucocele was an incidental finding.

Appendix↗

[Innervation of the human adrenal gland].

OBJECTIVE: To study the innervation of the human adrenal gland by immunohistochemical techniques using monoclonal antibodies against the 200-kDa phosphorylated neurofilament and S-100 protein, specific markers of the axons and Schwann cells, respectively. METHODS: 24 specimens of normal adrenal gland from patients that had undergone radical nephrectomy for a renal tumor were analyzed. The tissue was embedded in paraffin and prepared for analysis by immunohistochemical techniques with the indirect peroxidase method using primary monoclonal antibodies against the 200-kDA phosphorylated neurofilament and protein S-100. RESULTS: The nerves localized in the adrenal gland form a subcapsular plexus where branches arise that extend to the medulla and come into contact with the enterochromaffin cells and medullary neurons. The adrenal neurons are restricted to the medulla; they are dispersed or form ganglia. The satellite cells of the medullary ganglia and the sustentacular cells were positive for S-100. CONCLUSIONS: Most of the nerve fibers penetrate into the human adrenal gland, extending directly to the medulla apparently without coming into contact with the cells of the adrenal cortex and form similar connections to the synaptics with the chromaffin cells and the medullary neurons. The microganglia of the human adrenal gland are dispersed and comprised of few neurons.

Adrenal Glands↗

[Adrenal tuberculosis. Diagnosis using polymerase chain reaction].

OBJECTIVE: To present a case of a patient suffering from adrenocortical insufficiency (Addison's disease) and to demonstrate the utility of the polymerase chain reaction (PCR) in the diagnosis of adrenal cortex tuberculosis. METHODS/RESULTS: Herein we describe a patient with Addison's disease who had developed pulmonary tuberculosis a few years earlier. CT and PCR test were utilized in making the diagnosis. CONCLUSION: Although adrenocortical tuberculosis is uncommon today, it must be considered when evaluating adrenocortical insufficiency, especially if the patient has or has had tuberculosis. Although Mycobacterium tuberculosis might not be demonstrated by bacteriologic techniques, PCR can be useful in making the etiological diagnosis.

Addison Disease↗

[Pure prostatic leiomyoma].

We report a case of pure leiomyoma of the prostate, an uncommon benign tumor with a leiomyomatous component distinct from benign prostatic hyperplasia. The literature is reviewed and several considerations are put forward relative to the etiopathogenesis, clinical and anatomopathological features, differential diagnosis and prognosis of this tumor.

Aged↗

Granulomatous prostatitis.

Twenty cases of granulomatous prostatitis are presented. They were identified, histologically or cytologically, among 1,316 patients with prostatic pathology at the General Hospital of Asturias during a period of 3 years (Jan. 1984 to Dec. 1986). The etiology, histogenesis, clinical and morphological aspects, treatment and prognosis of the different types of granulomatous prostatitis, according to a classification by the authors, are discussed. The significance of the differentiation of granulomatous prostatitis from carcinoma is discussed. Fine-needle aspiration cytology (Franzen) is recommended as the diagnostic method of choice.

Biopsy, Needle↗