Biomedical subjects
Publications and source records attributed to J Goolsby.
Fluconazole concentrations in the serum and prostate of human volunteers undergoing transurethral resection for benign prostatic hypertrophy were measured. There was a high correlation (r = 0.783) between serum (mean = 6.6 micrograms/ml) and tissue (mean = 1.9 micrograms/g) fluconazole concentrations, and these data were used to construct a model for local tissue concentrations.
The measurement and tracking of patient satisfaction is an area of increasing importance today. Because of this importance, researchers have begun to more closely examine conceptual, operational and research design issues implicated in this measurement. In this context, this paper focuses on selected research design issues. Three key issues are discussed; namely, appropriate measures, item phrasing and data collection approaches. Issues, problem areas and suggested recommendations are provided. We hope our discussion will help future researchers achieve better and more meaningful measurement of patient satisfaction.
The association of mural thrombus with left ventricular aneurysm is well documented, though angiographic documentation of left ventricular thrombus can be difficult. The authors describe the unique appearance of the left ventricular cavity in 5 patients. In all cases, ventriculograms obtained in the right anterior oblique position showed a squared apex. In 2 patients this phenomenon was also demonstrated by radionuclide angiocardiography. All 5 patients were found to have left ventricular thrombus at operation or autopsy.