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Biomedical subjects

J Gotovac

Publications and source records attributed to J Gotovac.

10 recordsLinked to original sources
PubMed1991

Extracorporeal shockwave lithotripsy (ESWL)--a report on the first 500 patients.

This paper presents the results of the treatment of the first 500 patients treated with the second generation lithotriptor SIEMENS "LITHOSTAR". In 500 patients with 607 stones 521 treatments were performed in 799 sessions. Six months after the ESWL treatment 522 out of 607 stones (86%) were desintegrated completely, i.e. 87.2% of the patients were stone-free. The best results were obtained with solitary pelvic (95.51%) and ureteral stones (95.8%). In 52 patients (10.4%) complications due to obstruction were successfully solved by endoscopic procedures. These results clearly present ESWL as the best method in the treatment of urolithiasis patients.

Adolescent↗
PubMed1979

[Regeneration of defects in a small portion of the urinary bladder mucosa in experiments with guinea pigs].

Regeneration of the vesical mucosa begins from the remains of the bladder at the trigonum and urethra, and the author studied this regeneration in 30 rats. Epithelial regeneration began on the third day after formation of the defect. On the fifth day the entire defect was covered with transitional epithelium whose thickness did not exceed 1--2 cell layers. During the fifth week regeneration was complete. This experiment confirms the claim of Baker et al. the regeneration of the mucossa of the urinary bladder (except for the remaining mucosa of the trigonum and urethra) occurs via differentiation of pluripotential mesenchyme cells into transitional epithelium. During the experiment, the rats were given garamycin prophylactically. The very short regeneration time was probably due to the absence of any inflammatory process.

Animals↗
PubMed1978

[Surgical treatment of ureterocele].

From 1971 the authors operated on 6 patients with ureterocoele type B (Uson), using a modified Hutch-Chisholm method. Following the removal of the ureterocoele and reconstruction of the detrusor muscle, the hiatus of the ureter and the vesicular wall, the ureter is placed on the reconstructed muscle whereas its free end is fixed to the trigone. Covering the ureter with vesical mucosa is not necessary; in cases with large ureterocoeles that is not even possible. The regenerative capacity of the vesical mucosa is great and rapid and covers the intravesicular part of the ureter without causing damage to the ureteral orifice or to its valvular function. In all 6 patients the results were good at the control examination 3 to 6 years postoperatively.

Child, Preschool↗