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Biomedical subjects

J Goumans

Publications and source records attributed to J Goumans.

2 recordsLinked to original sources

[Superior-canal dehiscence syndrome].

Superior-canal dehiscence syndrome (SCDS) was first described in 1998; it manifests as symptoms of dizziness and oscillopsia when a sound or pressure stimulus is given to the ear concerned. SCDS is caused by dehiscence ofpetrosal bone overlying the superior, vertical semicircular canal, creating a 'third mobile window' to the labyrinth, in addition to the oval and round windows. Characteristic for this syndrome are eye movements with a vertical-torsion direction, evoked by sound stimuli, or pressure changes via the external ear canal and the Valsalva manoeuvre. The anomaly of the bony structure is visible on a CT scan. With its specific symptoms and characteristics, SCDS is an abnormality of the vestibular system that is relatively easy to diagnose. The syndrome may be treated with conservative or surgical means.

Ear, Middle↗

Angular and linear vestibulo-ocular responses in humans.

A new technique is introduced to measure linear and angular vestibulo-ocular responses in three dimensions. Using a three-dimensional motion platform, human subjects underwent whole-body rotations and translations. Eye movements were measured with an infrared video recording device and/or with scleral search coils. Subjects were tested with sinusoidal stimulation and impulses under light and dark conditions. The results show that for sinusoidal stimulation, torsion compensatory eye movements (roll stimulation) have a low gain compared to horizontal (yaw) and vertical (pitch) compensatory eye movements. With impulses, we reliably assessed gain and delay for rotations in yaw, pitch, and roll. Under this stimulus condition the gain for roll (torsion eye movements) was also low compared to yaw and pitch (horizontal and vertical eye movements). For translations, the gain of eye-movement responses varied between 0.7 and 1 in the light. In the dark, responses were lower and more variable.

Calibration↗