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J Grozdea

Publications and source records attributed to J Grozdea.

At least 55 records · Page 3Linked to original sources
PubMed1976

[Cytochemical aspects of human polynuclear neutrophils under the in vitro and in vivo action of TRH].

A TRH fixation in vitro occurs at the level of the human polynuclear neutrophil, which suggests putative membrane receptor (s) for the hypothalamic hormone. After TRH administration, enzyme modifications (myeloperoxydase, alkaline phosphatase) and metabolism changes (PAS, Sudan black) happen in vivo within the neutrophil, showing a functional activation of that blood cell. Two processes may be considered to explain those data: 1) the TRH is directly fixed, as observed in vitro; 2) a mediate hormone (TSH, T4, T3) is released capable of binding the granulocyte membrane.

Alkaline Phosphatase↗
PubMed1975

[Correlations between Ph 1 clone and leukocyte alkaline phosphatase on their associaton: chronic myeloid leukemia and pregnancy].

A biological [karyotype, leucocyte alkaline phosphatase (L.A.P.), haematimetry] and clinical study was performed on three women carriers of a chronic myaloid leukemia during their pregnancy (3 1/2 months, 6 1/2 months), or just after delivery. The results show : (1) a relation between the acuteness of the illness and a higher rate of L.A.P., probably secondary to pregnancy, and (2) a relation between the clinical evolution and the rate of Ph1 (+) cells.

Adult↗