[Multiple saccular aneurysms of the carotid system. Indications and results of the direct approach].
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to J Guerin.
Explore the source record for details and available documents.
Since 1978 we studied the different clinical prognostic factors on the survival of patients with malignant gliomas. The two main clinical factors of survival incidence are age and post-operative neurological status, or after anti-oedema treatment. We have established a clinical classification ; Group I : patients under 50 years with a good neurological status. Group II : Patients with one pejorative factor : age superior to 50 years, or poor neurological status. Group III : patients with two pejorative factors : age superior to 50 years and poor neurological status, or patients above 65 years. Our results confirm such an approach, by the study of 96 patients under a similar treatment. Histological grade may introduce a bias in such a study ; we have therefore studied the 55 patients whose multiform glioblastoma had an histological confirmation. This second analysis confirms the validity of our study, which is then the basis of the therapeutic approach to each group of patients.
Explore the source record for details and available documents.
Epidemiological data of 533 (42% male) agoraphobic patients referred to an anxiety disorder unit are reported. Comorbidity with mood disorders was high (48%). Therapeutic response was studied in 345 patients who received cognitive-behaviour therapy (CBT): 131 patients dropped out and 214 completed treatment. At post-test 71% of the completers were improved with maintenance of the gains in patients reevaluated at follow-up points ranging from 6 months to 18 years. Medication intake was significantly decreased. Intent to treat analysis of the whole CBT sample showed that 57% of the 345 patients were improved. Drop-outs were predicted by female sex and psychotic personality traits. This suggests that personality assessment should be carried out in agoraphobia and therapeutic interventions on personality considered in patients with disordered personality. The relatively low prevalence of women in the whole sample and their higher prevalence in drop-outs are discussed.