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Biomedical subjects

J Gundersen

Publications and source records attributed to J Gundersen.

At least 37 records · Page 2Linked to original sources
PubMed1978

Design and preliminary observations of National Cooperative Diethylstilbestrol Adenosis (DESAD) Project.

The National Cooperative Diethylstilbestrol Adenosis (DESAD) Project has completed the major portion of its enrollment phase with the examination of more than 3000 daughters of women taking synthetic nonsteroidal estrogens (denoted DES) during pregnancies occurring from the early 1940s to the mid-1960s. The aims of the Project are to fill urgent needs for information on the prevalence and incidence of structural and epithelial abnormalities or neoplastic changes and their complications in these young women. Participants are grouped by mode of entry as identified by prenatal record review (40.1%), documented as DES-exposed but walking in (25.1%), or referred (22.8%) to the DESAD Project for examination, and not documented as exposed but having gynecologic abnormalities typical of those associated with DES exposure (12.0%). This study cohort, in part having paired controls, will be examined annually for at least 5 years. Details of the design and selected preliminary findings are reported.

Adolescent↗
PubMed1975

Measurement of systolic blood pressure in fingers of newborn infants.

The systolic blood pressure in the index finger was measured using a minicuff and a strain gauge both placed around the finger. 122 measurements in four newborn infants were performed during monitoring in an incubator and the systolic blood pressure values obtained were compared with the simultaneously recorded intra-arterial blood pressure in the aorta. Good correlation between direct and indirect pressure values was found. An important advantage is that the measurements do not arouse the infants nor disturb their sleep. The procedure seems suited for further technical development and automatic measurements.

Blood Pressure↗
PubMed1975

The peripheral blood pressure in legs with venous ulcers.

Venous ulcers require effective compression treatment which is, however, contra-indicated in cases of arterial insufficiency. In elderly patients with typical venous ulcers the question arises whether they may have concomitant arterial insufficiency. In early studies is was proved that arterial insufficiency in the lower limbs may be diagnosed as a low systolic blood pressure in the great toe as compared with the systolic arm blood pressure. In the present investigation the systolic blood pressure in the great toe was measured in 48 patients with verified venous ulcers. The toe blood pressure and the pressure difference from arm to toe were studied and compared with the corresponding values in normal subjects. 35 patients had no evidence of arterial insufficiency, but in 13 cases signs of concomitant arterial insufficiency was found. The method of measuring the systolic blood pressure in the toes seems to be a simple and reliable method for estimating the degree of arterial insufficiency even in patients with chronic venous disease.

Aged↗