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Biomedical subjects

J H Arrington

Publications and source records attributed to J H Arrington.

5 recordsLinked to original sources
PubMed1989

Rheumatoid papules: lesions showing features of vasculitis and palisading granuloma.

Whether palisading granuloma formation occurs with leukocytoclastic vasculitis in rheumatoid nodules and in histopathologically similar conditions is debatable. Patients with high titers for rheumatoid factor and severe erosive rheumatoid arthritis are at risk for both rheumatoid vasculitis and rheumatoid nodules. A patient with all of these features developed a papular eruption. These papules showed clinicopathologic features both of leukocytoclastic vasculitis and of early palisading granuloma. Lesions resolved slowly with low-dose oral corticosteroid therapy. It is proposed that these lesions be called rheumatoid papules and that they may represent a link between vasculitis and the palisaded granulomatous reaction seen in rheumatoid nodules.

Biopsy, Needle↗
PubMed1987

Recurrent melanocytic nevi: clinical and histologic review of 175 cases.

Pigmented nevi, if excised incompletely, often recur and occasionally cause concern to the patient and the physician. In this study of 175 recurrent nevi from 173 patients, the clinical, gross, and microscopic features of recurrent nevi are described and criteria for diagnosis are developed. Rarely, recurrent nevi have atypical features that suggest malignant melanoma. The differential diagnosis entails clinical and histologic criteria that are presented.

Adolescent↗
PubMed1979

Thermal keratoses and squamous cell carcinoma in situ associated with erythema ab igne.

A 60-year-old black woman had a large hyperkeratotic lesion and multiple smaller hyperkeratotic papules and plaques on the lower part of her legs in areas of erythema ab igne. Histologic examination of the largest lesion showed hyperplastic carcinoma in situ and the multiple smaller lesions showed varying degrees of squamous cell atypia and dermal elastosis. Histologically, these lesions were identical to solar-induced atypia, indicating that squamous cell carcinoma arising in erythema ab igne may be biologically similar to actinic carcinoma. Discussed here are clinical and histologic features of the thermal-induced lesions and other types of thermal-induced carcinomas.

Carcinoma in Situ↗
PubMed1977

Plantar lentiginous melanoma: a distinctive variant of human cutaneous malignant melanoma.

The neoplastic system of human cutaneous melanoma includes three generaly recognized variants: lentigo maligna, superficial spreading melanoma, and nodular melanoma. Lentiginous melanomas other than lentigo maligna constitute a fourth group, of which plantar lentiginous melanoma qualifies as an anatomic subgroup. Histologically and clinically, plantar lentiginous melanoma (PLM) is characterized by a period of radial growth and often by one or more foci of regression. In 27 of 33 plantar melanomas, a characteristic lentiginous, radial component of melanocytic proliferation was noted. In the remaining six cases, histological material failed to document a radial component. Eighteen of the 27 patients with PLM were blacks, and 18 patients died of distant metastasis. Tumors invasive to level II did not metastasize, but at levels IV and V and in tumors with a high mitotic rate, the prognosis was poor. The presence of lymph node metastases at the time of initial therapy correlated with a poor prognosis group.

Aged↗