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Biomedical subjects

J H Axton

Publications and source records attributed to J H Axton.

At least 19 recordsLinked to original sources
PubMed1979

Galactosaemia in three Rhodesian infants.

The clinically relevant types of genetic galactosaemia involve deficiency of galactose-1-phosphate uridyltransferase (EC 2.7.7.12) or galactokinase (EC 2.7.1.6). Specific diagnosis is made by quantitative assay of these two enzymes. Seven Black patients were referred from Harare Hospital, Rhodesia, with features suggestive of galactosaemia. Enzyme assay identified classic homozygous transferase deficiency in 3 of these patients. The incidence in this population was calculated to be 1:52 000.

Clinical Enzyme Tests↗
PubMed1979

Measles and the state of nutrition.

The severity of an attack of measles is largely determined by the underlying state of nutrition at the time of the attack. Evidence is presented which suggests that, conversely, measles may be responsible for the precipitation of malnutrition in undernourished children, by a combination of several different mechanisms.

Child↗
PubMed1977

Effectiveness of nursing sisters in primary paediatric care.

A comparison was made of the management, by nursing sisters and a paediatrician, of 76 children attending primary care clinics. In 95% of consultations, the treatment and the presumed outcome of treatment were identical. The nursing sisters identified correctly all children for whom a second opinion was needed. If nursing sisters are responsible for primary care, they can be expected to refer approximately 10% of the children they see.

Diagnostic Errors↗
PubMed1977

Domiciliary management of simple femoral fractures in children.

Twenty-six children with a simple fracture of one femur were nursed at home while on gallows traction, under the supervision of health visitors. The average stay in hospital before they were allowed home on traction was 8,5 days. A control group of 28 children with similar fractures, who were nursed only in hospital, spent an average of 34 days in hospital. No complications of treatment were encountered in either group. It is suggested that when there is an efficient health visiting service, children with uncomplicated fractures of the femur can be nursed at home, with benefit to the hospital, the child, and his family.

Child↗
PubMed1976

A trial of oral oxamniquine in the treatment of Schistosoma infection in children.

Oral oxamniquine 800 mg/m2 body surface area/day in divided doses for 2 days, was given to 57 children with schistosomal infections. Haematological and biochemical tests suggest that this drug is safe, even in the presence of significant liver enlargement. Parasitological investigations in 32 children who were followed up for 1 month indicate that oxamniquine is effective in the treatment of S. mansoni infection, but that it has little effect on S. haematobium infection.

Adolescent↗
PubMed1975

Virus particles and gastro-enteritis in Black and White Children in Rhodesia.

Stools from Black and White children with gastroenteritis and from controls were investigated for potentially pathogenic agents by conventional virological and bacteriological methods and by electron microscopy. Isolations were obtained in 30 percent of cases but electron microscopy more than doubled the number of agents found. Orbiviruses were present in 40 percent of all cases, often in combination with other organisms. There was no difference between the Black and White groups.

Black or African American↗