Biomedical subjects
J H Durston
Publications and source records attributed to J H Durston.
Megaloblastic erythropoiesis and macrocytosis in patients on anticonvulsants.
The results of deoxyuridine suppression tests on the bone marrow cells of 14 patients on anticonvulsant drugs, 11 of whom had evidence of megaloblastic erythropoiesis, indicated that the megaloblastic changes and macrocytosis encountered in treated epileptics are often not caused either by folate deficiency or by drug-induced impairment of the 5, 10-methylenetetrahydrofolate-dependent methylation of deoxyuridylate to thymidylate. A folate-related abnormality in the methylation of deoxyuridylate was found in only two of the 11 patients with megaloblastic erythropoiesis.
Syphilitic myositis.
A case of myositis associated with secondary syphilis is described. Complete recovery occurred after antisyphilitic treatment.
The pattern of peripheral nerve regeneration induced by crush in rats with severe acrylamide neuropathy.
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Histochemistry of primate extraocular muscles and the changes of denervation.
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Relapsing encephalomyelitis.
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Blindness due to aneurysm of anterior communicating artery. With recovery following carotid ligation.
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Myasthenia gravis, Hashimoto's disease and pernicious anaemia.
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