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Biomedical subjects

J H Egleton

Publications and source records attributed to J H Egleton.

6 recordsLinked to original sources
PubMed1995

Comparative in vitro activity of furopenem against aerobic bacteria isolated from pediatric patients.

The in vitro activity of the oral penem furopenem (WY-49605, 545555, SUN5555, and ALP201) was tested against clinical bacteria isolated from pediatric patients. Furopenem was compared with clarithromycin, cefpodoxime, amoxicillin, amoxicillin-clavulanate, cefaclor, cefixime, and cefuroxime. Furopenem demonstrated consistent activity against Escherichia coli [minimum inhibitory concentration (MIC90) = 1.0 microgram/ml)] Klebsiella pneumoniae (MIC90 = 2.0 micrograms/ml), Salmonella enteriditis and Shigella spp. (MIC90 = 1.0 microgram/ml), and beta-lactamase-positive or -negative Haemophilus influenzae (MIC90 = 1.0 microgram/ml) and Moraella catarrhalis (MIC90 = 1.0 microgram/ml). Furopenem was also active against a number of the Gram-positive organisms tested including methicillin-susceptible Staphylococcus aureus and penicillin-susceptible Streptococcus pneumoniae. These results suggest a potential application for this agent in the treatment of children as outpatients.

Bacteria, Aerobic↗
PubMed1990

Evaluation of direct wet mount parasitological examination of preserved fecal specimens.

A retrospective study covering a 12-year period was performed to determine the contribution of the direct wet mount microscopic examination to the identification of intestinal parasites in preserved fecal material. It was determined that each of 898 specimens contained at least one parasite when processed by the direct wet mount, concentration, and trichrome staining procedures. Of these procedures, the direct wet mount examination was solely responsible for the identification of 45 (2.9%) of 1,581 parasites identified. This is in contrast to the 15.1 and 12.5% which were found exclusively by the concentration and trichrome methods, respectively. These percentages may vary, depending on the prevalence of parasites and the stages present in the stool specimen.

Animals↗
PubMed1987

Hemo-De as substitute for ethyl acetate in formalin-ethyl acetate concentration technique.

In comparative studies, Hemo-De (PMP Medical Industries, Inc., Irving, Tex.) was found to be a suitable replacement for ethyl acetate in the Formalin-ethyl acetate concentration technique. With essentially equivalent recovery rates for both procedures, the Formalin-Hemo-De concentration technique is considered to be the preferred technique because Hemo-De is less toxic and less flammable and does not present disposal problems, and its cost is approximately one-fourth that of ethyl acetate.

Acetates↗