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J H Goch

Publications and source records attributed to J H Goch.

102 records · Page 6Linked to original sources
PubMedDate not supplied

Non-invasive methods of atrial function evaluation in heart diseases.

The article describes four essential components (hemodynamic, bioelectrical, hormonal, metabolic) of atrial function. The role atria play in heart hemodynamic performance by virtue of their reservoir, conduit and active contractile function is emphasized. Next, the authors relate various non-invasive diagnostic methods in cardiology to the estimation of particular types of atrial function in physiological and in selected pathological conditions. Only non-invasive and easy accessible in clinical practice diagnostic methods are presented. The use of echocardiography for the evaluation of hemodynamic function of atria and left atrial appendage is particularly exposed.

Atrial Natriuretic Factor↗
PubMedDate not supplied

[Platelet aggregation in patients with coronary disease treated with nifedipine].

The effect of nifedipine on the aggregation of blood platelets has been studied in patients with coronary heart disease. The study involved 78 males, aged between 36 and 64 years (mean age 51 years). The level of aggregation was evaluated before and after a single nifedipine dose of 10 mg (in 15 patients) and of 20 mg (in 34 patients) as well as before and after the treatment with nifedipine (of 29 patient) with a daily dose of 30 mg for two weeks. Aggregation of blood platelets induced by adenosine--diphosphate in of concentrations 1 microM/ml and of 5 microM/ml were estimated by the Born method. It was found that nifedipine reduces the aggregation of the blood platelets in patients with coronary heart disease following single and long-term treatment.

Adult↗
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Myocardial contractility in healthy rabbits.

In 75 healthy rabbits the systolic times intervals (STI) and their indexes of the left-ventricle were determined for establishing the normal range of these values. In the analysis the effects of the heart rate on the values of these parameters were taken into account. A correlation was found between the heart rate and the QT interval (r = -0.8673), total electromechanical systole - QS2 (r = -0.5557), heart sounds interval - S1S2 (r = -5696), left ventricular ejection time - LVET (r = -0.4745), pre-ejection period - PEP (r = -2288), isovolumic contraction time - ICT (r = -0.2570). No correlation was found between the heart rate and the electromechanical delay - Q-1 (r = -0.0226).

Animals↗