Biomedical subjects
Publications and source records attributed to J H Hoekstra.
Fetal survival is possible even with very premature rupture of membranes followed by persisting oligohydramnios, secondary Potter facies and limb deformities. A case history is given with continuous amniotic fluid loss starting at 11+4 weeks, without development of pulmonary hypoplasia.
The view appears to be generally held that the survival chances of fetuses in cases of very early rupture of the membranes are low. We report a retrospective study of 12 pregnancies with prolonged rupture of the membranes less than or equal to 24 weeks menstrual age. There was no significant maternal morbidity. After birth special attention was given to respiratory problems, deformities and infections. Four children were born at menstrual age less than 26 weeks. In all cases an intrauterine infection was found (chorioamnionitis). The eight children born greater than or equal to 26 weeks had good chances of survival despite oligohydramnios (all) and deformities (four). Severe intrauterine infections were not present in this group. An expectant obstetric management in cases of very early prolonged rupture of the membranes seems justified.
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