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Biomedical subjects

J H Jacob

Publications and source records attributed to J H Jacob.

23 records · Page 2Linked to original sources
PubMed1985

[Screening for cancer of the upper aerodigestive tract in a high-risk population].

From the data collected in the Cancer Registry of Calvados, a screening program for neoplastic lesions of the whole upper digestive and respiratory tract was performed in a canton where esophageal cancer incidence is very high. 137 men underwent this examination for mouth, pharyngo-larynx and esophagus. None neoplastic lesion was revealed but histologic and cytologic swabs showed some abnormalities that are now being studied.

Adult↗
PubMed1985

Histology and ultrastructure of the human esophageal epithelium. I. Normal and parakeratotic epithelium.

The authors present a histological and ultrastructural analysis of normal and parakeratotic human esophageal epithelium. Parakeratosis is encountered frequently during routine examinations of noncancerous esophageal mucosa in patients with carcinoma of the esophagus. Morphologically, this alteration corresponds to an incomplete keratinization of the esophageal epithelium with an excessive accumulation of keratin microfilaments, nuclear maturation reaching the stages of pyknosis and lysis, and anomalies in surface cell desquamation.

Epithelium↗
PubMed1983

A study of the mechanism of the toluidine blue dye test.

Toluidine blue is commonly used by endoscopists as a screening test for squamous cell carcinoma. Little information is available on the mechanism of vital staining as it is not preserved by conventional fixation. By using a simple method to stabilize toluidine blue, the authors were able to study the action of the dye under the light and electron microscope. The findings are reported.

Carcinoma, Squamous Cell↗
PubMed1975

[The early differentiation of the perinotochordal connective tissue. A scanning and transmission electron microscopic study on chick embryos (author's transl)].

The early differentiation of the connective tissue was investigated in the perinotochordal zone of 2-3 day-old chick embryos. After characterizing the different tissue components by transmission electron microscopy, their arrangement and distribution were examined by SEM. The results are discussed with regard to the role of the extracellular material in embryonic tissue interactions.

Animals↗