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Biomedical subjects

J H Jensen

Publications and source records attributed to J H Jensen.

7 recordsLinked to original sources
PubMed1991

Treatment of recurrent acute tonsillitis with clindamycin. An alternative to tonsillectomy?

The failure of treatment with penicillin in patients suffering from acute beta-haemolytic streptococcus Group A tonsillitis, may be due to the presence of beta-lactamase-producing bacteria. Several studies indicate that treatment with clindamycin may prevent recurrence and thereby eliminate the need for tonsillectomy. In this prospective study, 54 patients with recurrent acute tonsillitis were investigated. 29 patients were treated with clindamycin, 150 mg 4 times daily for 10 days, while 25 patients received no antibiotic treatment and served as a control group. A significantly reduced number of episodes of acute tonsillitis (P less than 0.01) and of tonsillectomy (P less than 0.001) was found in the group of patients treated with clindamycin.

Acute Disease↗
PubMed1990

Topical application of decongestant in dysfunction of the Eustachian tube: a randomized, double-blind, placebo-controlled trial.

Thirty-six patients, aged 12-75 years, with dry, central tympanic membrane perforations and a negative Valsalva manouevre and/or a negative aspiration/deflation test, were included in a randomized, double-blind, placebo-controlled trial on the effect of a decongestant agent (xylometazoline chloride 0.1%) and placebo (saline 0.9%) applied directly to the pharyngeal opening of the Eustachian tube. Judged by the Valsalva manouevre, tubal patency was significantly improved after application of the active drug (P less than 0.003). In contrast, no effect was demonstrated by the aspiration test (P = 0.80) or the deflation test (P = 0.51). It is concluded that a topical decongestant improves Eustachian tube function but only at unphysiologically high pressures.

Administration, Topical↗
PubMed1979

Two cases of anomalies of the bronchi combined with cancer in the lung.

Two cases of right-sided bronchus anomalies are described. These represent two groups, stated in the literature to be the commonest anomalies, viz. displaced apical bronchus and bronchus cardiacus superior. The first case was combined with an epidermoid carcinoma localized to the displaced apical bronchus and was found during surgery. In the second case, the anomaly was diagnosed by bronchoscopy and verified by thoracotomy with bilobectomy for adenocarcinoma. Anomalies of these types should be borne in mind in the bronchoscopic assessment of the operability and treatment of benign and malignant pulmonary disease.

Bronchi↗
PubMed1975

Diagnosis and management of tuberculous cervical adenitis.

In a series of 133 patients with a primary diagnosis of tuberculosis admitted to the Naval Regional Medical Center, San Diego, Calif, during a four-year period from July 1967 to July 1971, 29 (16.7%) had extrapulmonary lymphadenitis. The cervical region was involved in 20 (68.7%) of these cases. This report reviews the history of scrofula and deals with specific diagnostic tests which are helpful in separating tuberculous adenitis from other masses found commonly in the neck. Excisional biopsy and methods of handling these specimens are stressed. The higher incidence of tuberculous lymphadenitis in dark-skinned individuals, especially Orientals, when compared with a similar population group with pulmonary tuberculosis is noted and theories for this stated.

Adult↗