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Biomedical subjects

J H Müller

Publications and source records attributed to J H Müller.

At least 37 records · Page 2Linked to original sources
PubMed1988

[Acute phlebographic diagnosis of thrombotic complications in gynecology and obstetrics].

From 1971 to April 1986 phlebography was performed in a total of 459 patients suspected clinically having an acute phlebothrombosis. From 112 female patients (24.4%) coming from the departments of gynaecology and obstetrics in 94 cases an acute or subacute phlebothrombotic process was proved phlebographically. The main age of these female patients was 29 +/- 11 years (17 to 76 years). A combined ileo-femoral-crural vein thrombosis in 44.7% was the most frequent localization and expansion, however, an isolated thrombotic process of pelvic veins was found in 25.6% only. A coincidence of the calculated age of thrombosis and clinical symptoms could be proved in 62 female patients (66%), but often the phlebographically calculated thrombus age was much longer than suspected by clinical symptoms alone. Foudroyant pulmonary embolism was observed in each fifth or sixth patient. The special technique of phlebographic investigation is discussed in detail with the judgement of a differentiated therapy of phlebothrombosis and pulmonary embolism.

Adolescent↗
PubMed1987

[Initial experience using percutaneous transluminal coronary angioplasty in the immediate management of acute myocardial infarct].

Reported in this paper is experience obtained from coronary diagnosis and coronary fibrinolysis in acute myocardial infarction. Local fibrinolysis was applied to 69 patients, with 2 X 75,000 units of streptokinase in 30 minutes being the dose for orientation. Percutaneous transluminal coronary angioplasty was added in those cases in which therapeutic fibrinolysis proved to be insufficient. An additional bypass operation was required by nine patients.

Angioplasty, Balloon↗
PubMed1986

The cost and appropriateness of health care technology in South Africa. A plea for the development of a local medical equipment industry.

Some of the main reasons for the increase in the cost of health care technology are summarized. Local problems in the health care delivery system are not being solved effectively by imported medical equipment. The expertise required for the local solution of problems is available in the RSA and should be developed further. A private-sector consortium with matching funding from the State should serve as a clearing house for developing and evaluating assessment criteria, promoting the use of existing cost-efficient medical technologies, and identifying obsolete and inappropriate ones. The formation of a local health care technology corporation should be considered seriously.

Costs and Cost Analysis↗
PubMed1986

[Arterial hemodynamics of kidney transplants after end-to-side and end-to-end anastomosis (experimental study in the dog)].

Arterial hemodynamics of end-to-side versus end-to-end anastomized kidney grafts were studied comparatively in anaesthetized dogs with bilateral autotransplants. Evaluating the data of mean pressure in the renal artery (Pm), amplitude of the pulse-pressure (delta P), maximal steepness of the pulse-pressure (dp/dtmax), maximal speed of the flow-waves (Vimax), planimetric percentage of positive and negative shares of the flow-curves and the resulting "effective" level, mean renal blood flow (Vtotal) and the amount of vascular resistance calculated from the quotient Pm/Vtotal, it was found that delta P, dp/dtmax, Vimax and Vtotal were significant higher immediately after transplantation using end-to-end anastomoses as compared with end-to-side anastomoses. However, controls following 4 months after the transplantation revealed normal hemodynamic findings and no differences in the course of anastomotic pulse curves were observed. The initial disparity in the hemodynamics of both types of anastomoses was refered to different modules of elasticity (E) in consequence of unequal lengths of anastomoses reflecting the pulse waves by increased peripheral resistance.

Animals↗
PubMed1985

[Diagnosis of primary hyperparathyroidism by selective determination of parathyroid hormones].

Due to a hypercalcaemia and changeably appearing hypercalciuria 13 patients with relapsing urolithiasis were under suspicion of a primary hyperparathyroidism. After selective sounding and withdrawal of blood from the cervical veins in all cases the determination of parathormones was performed and always an increased activity of parathormones was found. The exploration of the cervical region carried out could in 11 performed operations in 8 cases prove an adenoma and in 3 cases a hyperplasia as cause of hyperparathyroidism. A localization of the suspected adenoma was in 5 cases possible in combination with the angiography of the thyroid gland. By equally high activity in 3 cases no clear evidence was possible. An improvement of the diagnostics of localization might be achieved by supraselective sounding of the veins. On principle the authors recommend to perform a selective determination of parathormones before operation, which in case of need is to be supplemented by a selective angiography of the thyroid gland.

Adult↗
PubMed1984

[Results of local intracoronary fibrinolysis in acute myocardial infarct and the effects of reperfusion on the function of the left ventricle].

Out of 46 patients who had undergone acute coronary angiography in 41 a definitive acute myocardial infarction was present. In 31 complete and in 10 cases subtotal obliterations of the infarct-related coronary artery were found. 14 patients had a one-vessel-disease, 8 a two-vessel-disease, but 19 a three-vessel-disease. In these 41 patients with acute myocardial infarction a subsequent intracoronary fibrinolysis therapy with streptokinase or urokinase immediately followed, which was successful in 33 patients (80.5%). Coronarographically neither a recanalization or a marked improvement of luminal patency of the infarct-related coronary artery could be proved. In 4 patients an additional guidewire thrombus perforation was necessary. The intracoronary fibrinolysis lasted maximally 2 hours (average total dosage 121.000 +/- 45.000 U streptokinase) and was essentially well tolerated. Only 3 patients of the treatment group died. 20 patients underwent a repeated angiography on average 8 1/2 months after fibrinolysis therapy, out of this group in 10 successfully treated patients comparable quantitative angiographic investigations are present. Heart index, stroke volume and systolic ejection fraction improved significantly. The percental size of the non-contracting area of the myocardium decreased statistically significantly. The recanalized coronary arteries were still patent at control.

Cardiac Output↗
PubMed1984

[A model of chronic percutaneous blood sampling during subcutaneous transposition of the renal vein in heterotopic kidney transplants in the dog].

The operative techniques of subcutaneous transposition of the renal vein in the heterotopic canine kidney transplant model and of the carotid artery are described in detail. Following this procedure a chronic percutaneous access of the renal vein and carotid artery for investigations of the kidney transplant metabolism and blood pressure measurement respectively is possible.

Animals↗
PubMed1984

[Sclerotherapy].

Explore the source record for details and available documents.

Dose-Response Relationship, Drug↗
PubMed1983

[Treatment results following acute thrombophlebitis. A comparison between thrombectomy and fibrinolysis therapy].

In a retrospective study 55 patients suffering from acute phlebothrombosis were subjected to an examination in order to evaluate the long term results of treatment. Good results of treatment could be achieved for the compensated stages 0-II of the postthrombotic syndrome in 22 patients after thromboectomy and in 33 patients after fibrinolysis (82 or 85% respectively). The portion of bad results of both methods, in the decompensated stages III-IV of the postthrombotic syndrome, was high (18 or 15% respectively). In both methods there was only 1 patient in stage IV of the postthrombotic syndrome, i.e. the total study comprised only 2 patients suffering from a postthrombotic crural ulcer.

Acute Disease↗