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Biomedical subjects

J H Puls

Publications and source records attributed to J H Puls.

2 recordsLinked to original sources

The TICAS-RTCIP real time cell identification processor.

A preliminary model of a real time processing system, the TICAS-RTCIP (for Taxonomic Intra-Cellular Analytic System--Real Time Cell Identification Processor) has been disigned and is being tested under operational conditions, proving the substantial advantages of employing a network of microprocessors operating in parallel. The system is designed only to demonstrate the feasibility, while more extensive development and biologic testing will be required to assess general applicability to automated uterine cytology.

Computers

An automated device for the production of cell preparations suitable for automatic assessment.

A set of preparatory steps has been developed for the processing of clinical samples from the female genital tract onto microscopic slides suitable both for machine assessment and for regular microscopic evaluation. These steps involve the depositing of the cell sample in a collection fluid, the semi-automatic adjustment of cell concentration to about 30,000 cells per milliliter through a combination of transmittance and light scatter measurements, the dispersion of the sample by syringing, and the deposition of the cellular content onto microscope slides by centrifugation. These steps were designed so as not to allow loss of cells--except the lysis of erythrocytes--with the understanding that this condition entails the presence of 4--10 per cent cell aggregates in the final preparation.

Autoanalysis