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Biomedical subjects

J H Quinn

Publications and source records attributed to J H Quinn.

15 recordsLinked to original sources

The clinical effects of electrostimulation on salivary function of Sjögren's syndrome patients. A placebo controlled study.

A multi-center double-blind study of an electro-stimulator device was conducted to evaluate its ability to increase the production of saliva and reduce clinical symptomatology. A total of 77 Sjögren's syndrome patients at three centers were assigned to active devices (n = 40) or to placebo devices (n = 37). There were 2 male and 32 female patients assigned to active devices, and 1 male and 36 female patients assigned to placebo devices. The age range with the greatest number of patients was 60-69 years making up more than 31% of the study population. The selection criteria required the patients to have no greater than 0.2 g/min of whole salivary production (approximately 19% of normal salivary production). At the start of the study, the patients assigned the active device had a mean salivary production of 0.06 ml per min (6% of normal) and patients assigned placebo devices had a mean salivary production of 0.07 ml per min (7% of normal). There were three scheduled visits, 2 weeks apart, over a treatment period of 4 weeks. At all visits, the patients using active devices showed a statistically greater (P = 0.005 to 0.02) increase in the production of saliva than placebo patients. The study also evaluated the reduction of patients symptoms associated with xerostomia. Patients showed significant improvement in (1) difficulty in swallowing and (2) burning tongue (P = 0.008). Some patients on their initial visit had no response to the active device and did not show a significant response at subsequent visits.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent

Temporomandibular joint arthroscopy: a 6-year multicenter retrospective study of 4,831 joints.

Four health outcomes (range of motion, pain, diet, and disability) were measured in six diagnostic categories (internal derangement with closed lock, internal derangement with painful click, osteoarthritis, hypermobility, fibrous ankylosis, and arthralgia) in a 6-year retrospective multicenter study of 4,831 temporomandibular joints having undergone arthroscopic surgery. After arthroscopic surgery, 91.6% of all patients had good or excellent motion; 91.3% had good or excellent pain reduction; 90.6% had good or excellent ability to maintain a normal diet; and 92% had a good or excellent reduction in disability. These health outcomes compare favorably with all other known treatments for these conditions. Also, the surgical technique was relatively free of complications (4.4%).

Adolescent

Identification of prostaglandin E2 and leukotriene B4 in the synovial fluid of painful, dysfunctional temporomandibular joints.

It has been hypothesized that prostaglandin E2 (PGE2) and leukotriene B4 (LTB4) should be present in the synovial fluid of inflamed, dysfunctional temporomandibular joints. An assay to identify PGE2 and LTB4 and platelet-activating factor (PAF) was used, and a strong correlation between the levels of these lipid mediators of pain and inflammation and an index of clinical joint pathology was found.

Cartilage, Articular

Hydroxylapatite alveolar ridge reconstruction: clinical experiences, complications, and technical modifications.

Results of the reconstruction of 228 deficient alveolar ridges (208 patients) using hydroxylapatite with or without autogenous cancellous bone over a six-year period are reported. Complications included erosion, mental nerve neuropathy, migration and displacement of particles, overfill, and loose material. Modified techniques are presented that minimize the occurrence of these complications in Class III and IV ridge-deficient patients.

Adult

Preservation of the alveolar ridge with hydroxylapatite tooth root substitutes.

A total of 49 patients, who were followed for 3 to 31 months, have had 92 hydroxylapatite root implants placed in fresh extraction sockets without soft tissue closure. Hydroxylapatite root implants maintain approximately twice as much alveolar bone as the contralateral control sites without implants. It is believed that this method is a more effective and efficient procedure to preserve alveolar bone for retention of dentures than previously described procedures.

Alveolar Process

Aneurysmal atherosclerosis of the inferior labial artery with segmental arteriectomy.

A case of aneurysmal atherosclerosis of the inferior labial artery has been presented in which a segmental arteriectomy was performed to eliminate the possibility of involuntary trauma to the area, which could produce considerable hemorrhage. Psychologicall, the patient felt better by knowing that the mass was completely removed. Atherosclerosis should be considered when masses are found in the lips in elderly patients. It is thought that this lesion is common but has not been reported in the past.

Aneurysm

Trigeminal neuralgia: treatment by repetitive peripheral neurectomy. Supplemental report.

Peripheral neurectomy affords a conservative method of relieving the pain of trigeminal neuralgia. Although the relief is temporary, the procedure can be repeated when the pain recurs. At Ochsner Clinic, 162 neurectomies were performed on 88 patients between 1956 and 1971. This includes 112 neurectomies performed on 63 patients between 1956 and 1965 from the previous report. This form of treatment is particularly indicated for an aged or severely debilitated patient in whom craniotomy is contraindicated. The total pain-free period obtained from repeated peripheral neurectomies is significant and justifies the use of the procedure. The median pain-free period among the 88 patients was 41 months with a mean of 52.5 months.

Adult