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Biomedical subjects

J H Robertson

Publications and source records attributed to J H Robertson.

At least 55 records · Page 3Linked to original sources
PubMed1984

Comparative histological and radiographic effects of CO2 laser versus standard surgical anterior cervical discectomy in the dog.

The use of the CO2 laser in the extirpation of selected intracranial and spinal tumors has been shown to be of great benefit. The role of the CO2 laser as applied to other neurosurgical procedures has not been adequately explored or defined. The authors have compared the radiological and histological effects of performing anterior cervical discectomy with the CO2 laser to those of performing it by standard operative technique. Groups of laboratory dogs underwent anterior cervical discectomy performed in both operative fashions. The animals were killed and the operated disc spaces were examined radiographically and microscopically. Observations were made 1, 3, 5, 8, and 10 weeks postoperatively. Based upon these radiographic and microscopic evaluations, the authors were able to draw certain conclusions with respect to the use of the CO2 laser in performing anterior cervical discectomy.

Animals↗
PubMed1984

Closure of dural defects with proplast.

Defects of the dura mater, which are a source of cerebral spinal fluid leakage, may be produced by trauma and otologic and neurosurgical operations. Proplast was evaluated as a graft material to close dural defects in three animal models (cats). For comparison, temporalis fascia was similarly evaluated in an additional three cats. Microsurgical techniques were utilized to close the defects, and both materials successfully prevented cerebral spinal fluid leakage. Proplast, however, was judged superior when studied microscopically at three months. There was ingrowth of living dura into the Proplast and no evidence of inflammatory reaction.

Animals↗
PubMed1983

Stable E rosette-forming lymphocytes in the peripheral blood in non-Hodgkin's lymphoma.

The peripheral blood of 49 patients with non-Hodgkin's lymphoma and the same number of normal controls was examined for the presence of lymphocytes forming rosettes with sheep erythrocytes at 37 degrees C (stable E rosettes). Nineteen lymphoma patients but only five normal controls showed increased absolute levels. (P less than 0.01). There was no correlation between the occurrence of increased Stable E Rosette levels and the histological type of lymphoma but there appears to be a positive relationship with the presence of clinical stage III-IV disease at presentation (P = 0.011). It is suggested that stable E rosettes represent an immunological response to residual lymphoma in our patients. A longitudinal study in one patient is reported in detail to demonstrate the occurrence of fluctuations in stable E rosette levels coinciding with clinical changes.

Aged↗
PubMed1983

Comparative observations on effects of carbon dioxide laser-induced peripheral nerve lesions in the rat.

This study was conducted to determine any changes that might occur in the associated cell bodies and proximal nerve stumps of sciatic nerves cut with carbon dioxide laser radiation. These changes were then compared with the changes that occur when performed with cutting cautery and scalpel. Both the proximal stump and the related dorsal root ganglia were examined with light and electron microscopy. The sciatic nerve was severed in 10 rats with the carbon dioxide laser, a cutting cautery, or a scalpel. Subsequent histopathologic examinations revealed: (a) both myelin and axonal degeneration in scalpel cuts; (b) less degeneration of proximal stump myelin in laser cuts compared with cautery cuts; and (c) no abnormalities in the associated dorsal root ganglia of nerves cut with the carbon dioxide laser. It was concluded that both the carbon dioxide laser and cutting cautery result in less damage and degeneration than a scalpel when used to sever peripheral nerves. The difference between the laser and cautery lesions was more quantitative than qualitative in that both impart thermal energy to the nerve. The carbon dioxide laser resulted in the least amount of injury.

Animals↗
PubMed1983

Identification of cellular immunoglobulins in chronic lymphocytic leukaemia by immunoperoxidase staining.

An indirect immunoperoxidase technique has been used for visualisation of cellular immunoglobulins in chronic lymphocytic leukaemia. Baker's formol calcium was used as fixative. Monoclonal light and heavy chain patterns were demonstrated in 24 out of 27 cases. Only one case did not have any demonstrable immunoglobulins. The presence of alpha or gamma heavy chain immunoglobulin isotypes in leukaemic lymphocytes was found to be related to low mouse rosetting capacity (p less than 0.05).

Adult↗
PubMed1983

Use of the carbon dioxide laser for acoustic tumor surgery.

The carbon dioxide laser has been used clinically in both otorhinolaryngology and neurological surgery for approximately 10 years. Only recently, however, have technical modifications allowed its use with the operating microscope, providing the increased precision and control necessary for intracranial surgery. This paper reports the authors' experience with the carbon dioxide laser in the removal of acoustic tumors, details the surgical technique involved, and describes the advantages that may accompany the use of the laser in the removal of these difficult lesions.

Cranial Nerve Neoplasms↗
PubMed1983

Sacral plexus nerve sheath tumor: case report.

A young woman with chronic sciatica was found to have an intrapelvic sacral plexus nerve sheath tumor. Computed tomography of the pelvis was used to delineate this unusual site of tumor development. The case report and a discussion of pelvic nerve sheath tumors are presented.

Adult↗
PubMed1983

Acoustic tumor management--combined approach surgery with CO2 laser.

Our experience in surgical treatment of 105 patients with cerebellopontine angle tumors is reported. Major emphasis is placed on a combined surgical approach and use of the CO2 laser. Our approach to diagnosis is also emphasized, as is the method we have used in compiling and collecting the data resulting from the study. Postoperative results and complications are reported and discussed.

Adult↗
PubMed1982

Use of the carbon dioxide laser in the operative management of intracranial meningiomas: a report of twenty cases.

This study presents 20 cases of meningioma of various intracranial locations, all of which were removed with the carbon dioxide surgical laser system. The carbon dioxide laser is contrasted with other means of meningioma removal to emphasize the advantages of this new technology. These advantages include: (a) the ability to operate with smaller exposures, (b)reduced brain retraction, (c) a reduced amount of mechanical manipulation by vaporizing the tumor mass, (d) vaporization of the dural attachment after the removal of tumor, (e) improved operative precision, and (f) decreased intraoperative significant advancement in the ability to remove meningiomas that might prove difficult to extirpate by conventional means.

Adult↗
PubMed1982

Neuroradiological detection of small and intracanalicular acoustic tumors: an emphasis on CO2 contrast-enhanced computed tomographic cisternography.

Seventy patients suspected clinically of having an acoustic tumor were evaluated using the computed tomographic (CT) scan as the initial neuroradiological procedure, followed by CO2 contrast CT cisternography in cases where the intravenous contrast-enhanced scan did not reveal any lesion. Forty-eight gas CT cisternograms revealed 10 small acoustic tumors, 2 of which were totally intracanalicular. The authors present a review of the basic CT anatomy of the temporal bone as it relates to acoustic tumors. Based upon the ease of performance of the procedure, the low postexamination morbidity, and the excellent diagnostic results, CO2 CT cisternography is recommended as the procedure of choice in the diagnosis of small and intracanalicular acoustic tumors.

Adult↗