[Radiation burden; keeping one's distance is best].
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Biomedical subjects
Publications and source records attributed to J H Ruijs.
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Lymphography and abdominal CT were performed in 78 patients staged for Hodgkin's disease. In 82% of all patients, both examinations agreed on the presence or absence of lymph node involvement. In the group of 39 patients undergoing lymphography prior to CT, the agreement was 90%. In the group of 39 patients with lymphography following CT, the agreement was 74%. In 50% of the patients with discrepant findings, lymphography revealed abnormal nodes compared with CT. Lymphography was abnormal in 26% of patients with a normal CT scan as the first examination, and in 9% of patients with a normal CT scan as the second examination. It is concluded that lymphography is more reliable than CT in the examination of the abdomen. CT performed after a normal or an abnormal lymphogram adds little additional information. When CT is preferred as the initial investigation in staging Hodgkin's disease, lymphography only adds significant information if the CT scan is normal or equivocal.
The ability to distinguish between intra-abdominal and subcutaneous abdominal fat may be important in epidemiologic and clinical research. In this study anthropometric measurements were taken from 71 men and 34 women presenting for routine computed tomography (CT). Areas of abdominal fat were calculated from CT scans made at the level of the L4 vertebra. The amounts of intra-abdominal and subcutaneous abdominal fat could be accurately predicted from several circumferences, skinfold measurements, body mass index, and age (R2 ranged from 0.79 to 0.84). In addition, it was found that the area of intra-abdominal fat on the CT scan was related to the waist:hip circumference ratio (r = 0.75 in men, r = 0.55 in women) and to the waist:thigh circumference ratio (r = 0.55 in men, r = 0.70 in women). The correlations of the circumference ratios with the areas of subcutaneous fat were invariably lower.
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To find out whether MR imaging is contraindicated in patients with metallic implants or can be a routine diagnostic procedure, MR investigations in 18 patients with 22 Charnley-Müller total hip prostheses were performed on a 0.5 T Gyroscan S 5, Philips. No adverse reactions during or post MR investigation were encountered. The imaging of the soft tissue was superior to CT and showed less distortion. The diagnosis of loosening, by detection of demarcation lines at the interfaces was at its best in the distal part of the femoral stem prosthesis and was poor in the acetabular component and in the upper part of the stem prosthesis due to artifacts.
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The preliminary results are presented of a comparative study between MRI and CT in 150 patients from the University Hospital Utrecht. The purpose is through a prospective study to make more definitive assessments about the role and the value of MRI in the region of the brain and cervical spine. If compared with CT, no abnormalities were missed with MRI in 150 cases; MRI detected more lesions than CT, and often more information was provided by MRI. Spin-echo pulse sequence with long multiple echoes and short repetition time proved to be a sensitive detection method with sufficient tissue characterization for diagnosis. In the opinion of the authors, MRI should be the first step in detecting abnormalities of the brain and cervical spine.
A calculation of the costs of magnetic resonance (MR) using a machine with a field strength of 0.5 and 1.5 T is presented for the Netherlands. The costs per patient are 1,000 Dfl. and approximately 1,200 Dfl., respectively. Because the total number of MRI facilities in the Netherlands is strictly limited, also the costs of scientific research in the field of MRI have to be taken into account. It is possible to calculate the hourly costs of research on a time-sharing basis for a 1.5-Tesla machine. Combining patient care and scientific research on one machine has a reciprocal influence on the costs.
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