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Biomedical subjects

J H Sautter

Publications and source records attributed to J H Sautter.

At least 19 recordsLinked to original sources

Anemia and osteopetrosis in a dog.

A 1-year-old, male Australian Shepherd Dog with consanguineous parents was discovered to have severe nonregenerative anemia associated with osteopetrosis. Diagnosis of the bone abnormality was established by skeletal radiography and microscopic examination of a rib biopsy specimen. The anemia was attributed to failure to develop normal marrow cavities combined with failure of extramedullary erythropoiesis. Although blood transfusions sustained the dog's life for 15 months, the dog died of a hemolytic transfusion reaction.

Anemia↗

Susceptibility of turkeys to Georgia strain of Marek's disease virus of chicken origin.

Two experiments were conducted to study the susceptibility of turkeys to Georgia strain of Marek's disease virus (MDV). One-day-old chickens and turkeys were experimentally inoculated with Marek's disease (MD) infective plasma (experiment 1) or tumor homogenate (experiment 2) and raised in isolation for 29 weeks. The MDV inoculums were pathogenic for chickens and turkeys and caused high mortality (chickens, 100% and turkeys, 70%). Macroscopic lesions of MD were observed in liver, spleen, lungs, proventriculus, and other viscereal organs. Microscopically, affected tissues were infiltrated with the pleomorphic population of neoplastic lymphocytes. Uninoculated turkeys did not show gross or microscopic lesion of MD. The MDV was reisolated from the experimentally inoculated, but not from the uninoculated, chickens and turkeys. Antibodies to MDV were detected in experimentally infected chickens. Uninoculated chickens and all turkeys lacked precipitating antibodies to MDV. The present study suggests that turkeys are highly susceptible to experimental infection with GA strain of MDV.

Animals↗

Gastric neoplasms in the dog: a report of 20 cases.

Twenty dogs with gastric tumors were admitted to the University of Minnesota Veterinary Hospital and Diagnostic Laboratory from 1951 to 1974. The tumors included 14 carcinomas, 3 lymphosarcomas, 2 leiomyomas, and 1 leiomyosarcoma. The carcinomas were categorized morphologically as carcinoma (5), adenocarcinoma (2), scirrhous carcinoma (5), and scirrhous adenocarcinoma (2). Most of the tumors were located in the body and pylorus. Ulceration occurred in 11 dogs, with 2 ulcers penetrating and resulting in peritonitis. Metastasis occurred in 4 of the dogs. The mean age of the dogs was 9.7 years. The male-to-female ratio was 12 to 8. There was no significant breed predominance. The mean duration of illness was 2.14 months. Radiographic features were consistent with gastric neoplasia in 2 of 6 dogs radiographed.

Adenocarcinoma↗

Experimental enteric colibacillosis in piglets.

Eleven of 20 piglets inoculated orally with Escherichia coli:0101:KU460(A):NM and one of 18 piglets inoculated orally with E. coli:08:K87, K88a, b:H19 developed enteric colibacillosis. Successful reproduction of the disease was associated with recovery of a dense growth in a nearly pure culture of the inoculated strain from the feces. Piglets which remained clinically normal had none, or very few, of the inoculated strain in their feces. Seventeen control piglets inoculated orally with the non-enteropathogenic E. coli:043:K -:H28 remained normal.

Animals↗