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Biomedical subjects

J H Scheibel

Publications and source records attributed to J H Scheibel.

39 records · Page 3Linked to original sources

Treatment of chlamydial urethritis in men and Chlamydia trachomatis-positive female partners: comparison of erythromycin and tetracycline in treatment courses of one week.

Seventy-one consecutive men who had Chlamydia trachomatis-positive nongonococcal urethritis were assigned randomly to treatment for one week with either tetracycline or erythromycin (1g daily). Seventy men completed the study. At follow-up, there were two therapeutic failures among 36 patients treated with erythromycin, and two failures among 34 patients treated with tetracycline. Twenty-four C. trachomatis-positive female contacts were randomly assigned to treatment regimens similar to those of the men. There was one treatment failure among 12 women treated with erythromycin, and no failure among 12 treated with tetracycline. In this study the urethral smears contained fewer than five leukocytes per high-power field in 16% of the C. trachomatis-positive men with symptoms suggestive of urethritis.

Adolescent↗

Etiology of acute epididymitis presenting in a venereal disease clinic.

Sixteen patients aged 19-42 years and suffering from acute epididymitis were investigated. In twelve patients evidence of acute epididymitis developed without premonitory urethral symptoms. The only microbiologic finding for ten patients was Chlamydia trachomatis; both C. trachomatis and Neisseria gonorrhoeae were isolated from four patients. Two patients, who had recently had antibiotic treatment, harbored neither of these microorganisms. These observations indicate that C. trachomatis must be considered a dominant cause of acute epididymitis in the younger age groups. This fact has implications for the choice of treatment (erythromycin or tetracycline) and the investigations and treatment of sexual contacts.

Acute Disease↗