The relationship of allergies to hypertension and other chronic diseases: some methodologic considerations.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to J H Stebbings.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Body radon daughter contamination reflects relative individual respiratory exposures to radon daughters; counts can be related both to household radon levels and to lung cancer risk factors such as sex and tobacco smoking. Radon daughters were counted by gamma spectroscopy from 180 adult residents of eastern Pennsylvania. A seven-position, 35-min scan was conducted in a mobile body counter, generally during afternoon or evening hours. Track-etch detectors for household radon were distributed, and were recovered from 80% of the subjects. Over 75% of the population had environmentally enhanced radon daughter contamination. House radon levels were strongly related, as anticipated, to radon daughter contamination in the 112 subjects for whom both sets of measurements were available (p less than .001); basement measurements were as strongly related to personal contamination as were living area measurements; bedroom measurements were slightly more strongly correlated. Both sex (p less than .02) and cigarette smoking (p less than .01) significantly modified the relationships, after nonlinear adjustment for travel times. Using a logarithmic model, a given house living-area radon level was associated in females with body contamination by radon daughters 2-3 times that in males. Nonsmokers had 2-4 times higher levels of contamination than smokers. Results are for the total of internal and external contamination, these being highly correlated in preliminary experiments. Time usage and activity patterns of the subjects are believed to be important in explaining these findings, and may become important variables in radon risk assessment.
The classic health effects of occupational exposure to radium include osteosarcomas and fibrosarcomas of bone, carcinomas of paranasal sinuses and mastoid air cells, and microscopically and radiographically evident lesions of bone, along with fractures in highly exposed individuals. Among probable effects are breast cancer and acceleration of cataracts. Thyroid carcinoma is a possible high-dose effect. Leukemia is likely related to employment in the radium industry. Multiple myeloma and excess lung cancer may have resulted from high gamma radiation and radon exposures rather than from internal radium. At high doses, impairment of fertility has occurred. Further investigations of effects on the cardiovascular system and hearing, and on fracture-related disability very late in life, are needed.
Explore the source record for details and available documents.